Recombinant Rotavirus A Outer capsid protein VP4, partial
Cat# MBS1237257-0,1mg-E
Size : 0.1mg(E-Coli)
Brand : MyBiosource
Contact local distributor :
Phone : +1 850 650 7790
Outer Capsid Protein VP4 Rotavirus A Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1237257Spike-forming protein that mediates virion attachment to the host epithelial cell receptors and plays a major role in cell penetration, determination of host range restriction and virulence. Rotavirus entry into the host cell probably involves multiple… More details
Product Overview
Online Datasheet in PDFProduct Name
Outer capsid protein VP4, Recombinant Protein
Full Product Name
Recombinant Rotavirus A Outer capsid protein VP4, partial
Sequence
AQVSEDIIIS KTSLWKEMQY NRDIIIRFKF NNSIIKLGGL GYKWSEISFK AANYQYNYLR DGEQVTAHTT CSVNGVNNFS YNGGLLPTHF SISRYEVIKE NSYVYVDYWD DSQAFRNMVY VRSLAANLNS VKCSGGNYNF QMPVGAWPVM SGGAVSLHFA GVTLSTQFTD FVSLNSLRFR FSLTVEEPPF SILRTRVSGL YGLPASNPNS GHEYYEIAGR FSLISLVPSN DDY
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Molecular Weight
28.3 kDa
Sequence Positions
247-479aa; Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Product References and Citations for Outer capsid protein VP4 recombinant protein
Sequence of the fourth gene of human rotaviruses recovered from asymptomatic or symptomatic infections.Gorziglia M., Green K.Y., Nishikawa K., Taniguchi K., Jones R.W., Kapikian A.Z., Chanock R.M.J. Virol. 62:2978-2984(1988) Identification of two independent neutralization domains on the VP4 trypsin cleavage products VP5* and VP8* of human rotavirus ST3.Padilla-Noriega L., Dunn S.J., Lopez S., Greenberg H.B., Arias C.F.Virology 206:148-154(1995) Group A human rotavirus genomics evidence that gene constellations are influenced by viral protein interactions.Heiman E.M., McDonald S.M., Barro M., Taraporewala Z.F., Bar-Magen T., Patton J.T.J. Virol. 82:11106-11116(2008) Conservation of amino acid sequence of VP8 and cleavage region of 84-kDa outer capsid protein among rotaviruses recovered from asymptomatic neonatal infection.Gorziglia M., Hoshino Y., Buckler-White A., Blumentals I., Glass R., Flores J., Kapikian A.Z., Chanock R.M.Proc. Natl. Acad. Sci. U.S.A. 83:7039-7043(1986)
Other Notes
Small volumes of Outer capsid protein VP4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Outer capsid protein VP4 purchase
MBS1237257 is a recombinant protein targeting Outer capsid protein VP4. Also known as Recombinant Rotavirus A Outer capsid protein VP4, partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.
Additional Details
NCBI/Uniprot data below describe general gene information for Outer capsid protein VP4. It may not necessarily be applicable to this product.
NCBI Official Full Name
Outer capsid protein VP4
UniProt Protein Name
Outer capsid protein VP4
UniProt Synonym Protein Names
Hemagglutinin
Protein Family
Outer capsid protein
UniProt Entry Name
VP4_ROTHT
UniProt Comments for Outer capsid protein VP4
Spike-forming protein that mediates virion attachment to the host epithelial cell receptors and plays a major role in cell penetration, determination of host range restriction and virulence. Rotavirus entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. According to the considered strain, VP4 seems to essentially target sialic acid and/or the integrin heterodimer ITGA2/ITGB1 ().
Show more Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
You might also be interested by the following products:
Cat#
Description
Cond.
Price Bef. VAT