ROR2 Antibody
Cat# MBS8582382-0,1mL-FITC
Size : 0.1mL(FITC)
Brand : MyBiosource
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Phone : +1 850 650 7790
ROR2 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582382MBS8582382 is an antibody targeting ROR2. Also known as ROR2 Antibody. Reactive in Human, Bovine, Dog, Sheep. Host: Rabbit. Rabbit polyclonal antibody to ROR2 More details
Product Overview
Online Datasheet in PDFProduct Name
ROR2, Polyclonal Antibody
Full Product Name
ROR2 Antibody
Product Gene Name
anti-ROR2 antibody
Product Synonym Names
NTRKR2; Tyrosine-protein kinase transmembrane receptor ROR2; Neurotrophic tyrosine kinase, receptor-related 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Bovine, Dog, Sheep
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of ROR2 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
943
OMIM
phenotype 602337
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ROR2. The exact sequence is proprietary.
Product Categories/Family for anti-ROR2 antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ROR2 antibody
Western Blot (WB)
Application Notes for anti-ROR2 antibody
WB: 1:500-1:1000
Other Notes
Small volumes of anti-ROR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for ROR2. It may not necessarily be applicable to this product.
NCBI Official Full Name
Tyrosine-protein kinase transmembrane receptor ROR2
NCBI Official Synonym Full Names
receptor tyrosine kinase-like orphan receptor 2
NCBI Official Symbol
ROR2
NCBI Official Synonym Symbols
BDB; BDB1; NTRKR2
UniProt Protein Name
Tyrosine-protein kinase transmembrane receptor ROR2
UniProt Synonym Protein Names
Neurotrophic tyrosine kinase, receptor-related 2
Protein Family
Tyrosine-protein kinase transmembrane receptor
UniProt Gene Name
ROR2
UniProt Synonym Gene Names
NTRKR2
UniProt Entry Name
ROR2_HUMAN
NCBI Protein Information
tyrosine-protein kinase transmembrane receptor ROR2; neurotrophic tyrosine kinase receptor-related 2
NCBI Summary for ROR2
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for ROR2
ROR2: a receptor tyrosine kinase of the ROR family. May be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.
Protein type: Protein kinase, TK; Membrane protein, integral; Kinase, protein; Protein kinase, tyrosine (receptor); EC 2.7.10.1; TK group; Ror family
Chromosomal Location of Human Ortholog: 9q22
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: Wnt-protein binding; protein binding; frizzled binding; transmembrane receptor protein tyrosine kinase activity; ATP binding
Biological Process: somitogenesis; inner ear morphogenesis; peptidyl-tyrosine phosphorylation; Wnt receptor signaling pathway, planar cell polarity pathway; multicellular organismal development; positive regulation of transcription, DNA-dependent; signal transduction; negative regulation of cell proliferation; Wnt receptor signaling pathway, calcium modulating pathway; JNK cascade; cell differentiation; transmembrane receptor protein tyrosine kinase signaling pathway; cartilage condensation; embryonic genitalia morphogenesis; positive regulation of cell migration
Disease: Robinow Syndrome, Autosomal Recessive; Brachydactyly, Type B1
Show more Protein type: Protein kinase, TK; Membrane protein, integral; Kinase, protein; Protein kinase, tyrosine (receptor); EC 2.7.10.1; TK group; Ror family
Chromosomal Location of Human Ortholog: 9q22
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: Wnt-protein binding; protein binding; frizzled binding; transmembrane receptor protein tyrosine kinase activity; ATP binding
Biological Process: somitogenesis; inner ear morphogenesis; peptidyl-tyrosine phosphorylation; Wnt receptor signaling pathway, planar cell polarity pathway; multicellular organismal development; positive regulation of transcription, DNA-dependent; signal transduction; negative regulation of cell proliferation; Wnt receptor signaling pathway, calcium modulating pathway; JNK cascade; cell differentiation; transmembrane receptor protein tyrosine kinase signaling pathway; cartilage condensation; embryonic genitalia morphogenesis; positive regulation of cell migration
Disease: Robinow Syndrome, Autosomal Recessive; Brachydactyly, Type B1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-ROR2 antibody
| Reference Product | PubMed Publications |
|---|---|
| WNT5A antibody | >121 publications with ROR2 and WNT5A |
| FZD5 antibody | >10 publications with ROR2 and FZD5 |
| FZD2 antibody | >9 publications with ROR2 and FZD2 |
| GDF5 antibody | >5 publications with ROR2 and GDF5 |
| MAGED1 antibody | >2 publications with ROR2 and MAGED1 |
| NOG antibody | >2 publications with ROR2 and NOG |
| WNT16 antibody | >1 publications with ROR2 and WNT16 |
Pathways associated with anti-ROR2 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Cardiac Progenitor Differentiation Pathway antibodies | Cardiac Progenitor Differentiation Pathway Diagram |
| Noncanonical Wnt Signaling Pathway antibodies | Noncanonical Wnt Signaling Pathway Diagram |
| PCP/CE Pathway antibodies | PCP/CE Pathway Diagram |
| Signal Transduction Pathway antibodies | Signal Transduction Pathway Diagram |
| Signaling By Wnt Pathway antibodies | Signaling By Wnt Pathway Diagram |
| WNT5A-dependent Internalization Of FZD2, FZD5 And ROR2 Pathway antibodies | WNT5A-dependent Internalization Of FZD2, FZD5 And ROR2 Pathway Diagram |
| Wnt Signaling Pathway NetPath antibodies | Wnt Signaling Pathway NetPath Diagram |
| Wnt Signaling Network Pathway antibodies | Wnt Signaling Network Pathway Diagram |
| Beta-catenin Independent WNT Signaling Pathway antibodies | Beta-catenin Independent WNT Signaling Pathway Diagram |
Diseases associated with anti-ROR2 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Abnormalities, Multiple Antibodies | >23 publications with ROR2 and Abnormalities, Multiple |
| Adenocarcinoma Antibodies | >16 publications with ROR2 and Adenocarcinoma |
| Bone Diseases, Developmental Antibodies | >15 publications with ROR2 and Bone Diseases, Developmental |
| Inflammation Antibodies | >8 publications with ROR2 and Inflammation |
| Neoplasm Metastasis Antibodies | >8 publications with ROR2 and Neoplasm Metastasis |
| Embryo Loss Antibodies | >7 publications with ROR2 and Embryo Loss |
| Liver Neoplasms Antibodies | >6 publications with ROR2 and Liver Neoplasms |
| Kidney Diseases Antibodies | >6 publications with ROR2 and Kidney Diseases |
| Necrosis Antibodies | >5 publications with ROR2 and Necrosis |
| Breast Neoplasms Antibodies | >5 publications with ROR2 and Breast Neoplasms |
Organs/Tissues associated with anti-ROR2 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Lung Antibodies | >17 publications with ROR2 and Lung |
| Heart Antibodies | >15 publications with ROR2 and Heart |
| Intestine Antibodies | >11 publications with ROR2 and Intestine |
| Eye Antibodies | >10 publications with ROR2 and Eye |
| Stomach Antibodies | >9 publications with ROR2 and Stomach |
| Uterus Antibodies | >5 publications with ROR2 and Uterus |
| Testis Antibodies | >3 publications with ROR2 and Testis |