OASG04724 | RPS6KA5 Antibody Biovalley

Datasheets/Manuals	Printable datasheet for anti-RPS6KA5 (OASG04724) antibody

Product Info
Predicted Species Reactivity	Human, Mouse, Monkey
Product Format	Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality	Polyclonal
Isotype	IgG
Host	Rabbit
Application	WB, IHC
Reconstitution and Storage	Store at -20C. Avoid repeated freeze/thaw cycles.
Immunogen	Synthesized peptide derived from human MSK1 around the non-phosphorylation site of S360. Location: 300-380aa.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Specificity	MSK1 Polyclonal Antibody detects endogenous levels of MSK1 protein.
Application Info	WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Gene Symbol	RPS6KA5
Gene Full Name	ribosomal protein S6 kinase, 90kDa, polypeptide 5
Alias Symbols	MSK1, RLPK, MSPK1
NCBI Gene Id	9252; 73086;
Uniprot ID	O75582, Q8C050
Molecular Weight	90 kDa

Protein interactions

<<<<

Biological pathways

Name	# of Products
Axon guidance	739
Epidermal growth factor receptor signaling pathway	240
Histone H2A-S1 phosphorylation	1
Histone H3-S10 phosphorylation	2
Histone H3-S28 phosphorylation	2
Inflammatory response	911
Innate immune response	905
Interleukin-1-mediated signaling pathway	31
MyD88-dependent toll-like receptor signaling pathway	331
MyD88-independent toll-like receptor signaling pathway	288
Negative regulation of cytokine production	5
Negative regulation of transcription, DNA-dependent	660
Nerve growth factor receptor signaling pathway	602
Positive regulation of CREB transcription factor activity	26
Positive regulation of histone acetylation	33
Positive regulation of histone phosphorylation	21
Positive regulation of NF-kappaB transcription factor activity	346
Positive regulation of transcription from RNA polymerase II promoter	1210
Stress-activated MAPK cascade	207
Toll signaling pathway	369
Toll-like receptor 1 signaling pathway	309
Toll-like receptor 2 signaling pathway	309
Toll-like receptor 3 signaling pathway	272
Toll-like receptor 4 signaling pathway	330

Biological process

Name	# of Products
Axon guidance	286
Epidermal growth factor receptor signaling pathway	124
Histone H2A-S1 phosphorylation	1
Histone H3-S10 phosphorylation	2
Histone H3-S28 phosphorylation	2
Histone phosphorylation	5
Inflammatory response	339
Innate immune response	300
Interleukin-1-mediated signaling pathway	19
Intracellular protein kinase cascade	91
MyD88-dependent toll-like receptor signaling pathway	65
MyD88-independent toll-like receptor signaling pathway	56
Negative regulation of cytokine production	8
Negative regulation of transcription, DNA-dependent	520
Nerve growth factor receptor signaling pathway	173
Positive regulation of CREB transcription factor activity	14
Positive regulation of histone acetylation	21
Positive regulation of histone phosphorylation	7
Positive regulation of NF-kappaB transcription factor activity	135
Positive regulation of transcription from RNA polymerase II promoter	968
Protein phosphorylation	451
Regulation of transcription, DNA-dependent	1734
Response to external stimulus	8
Response to stress	160
Stress-activated MAPK cascade	47
Toll signaling pathway	66
Toll-like receptor 1 signaling pathway	59
Toll-like receptor 2 signaling pathway	61
Toll-like receptor 3 signaling pathway	54
Toll-like receptor 4 signaling pathway	64
Toll-like receptor signaling pathway	71
TRIF-dependent toll-like receptor signaling pathway	53

Cellular components

Protein function

Name	# of Products
ATP binding	2814
Magnesium ion binding	352
Nucleotide binding	3928
Protein binding	12191
Protein kinase activity	636
Protein serine/threonine kinase activity	738

RPS6KA5 Antibody