SUMO2, Xenopus, NT (sumo2-a, smt3h2, Small ubiquitin-related modifier 2-A)

Cat# 042478-200ul

Size : 200ul

Brand : US Biological

Contact local distributor :


Phone : +1 850 650 7790


042478 SUMO2, Xenopus, NT (sumo2-a, smt3h2, Small ubiquitin-related modifier 2-A)

Clone Type
Polyclonal
Host
rabbit
Source
Xenopus
Swiss Prot
Q7ZTK7
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Gene #
sumo2-a
Shipping Temp
Blue Ice
Storage Temp
-20°C

SUMO2 is a ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. SUMO2 does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. This protein plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS isoforms 1-4.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: Xenopus|Concentration: Not Determined |Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.|Purity: Purified by Protein A affinity chromatography.|Immunogen: Xenopus SUMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Xenopus SUMO2.|Specificity: X||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Xenopus SUMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Xenopus SUMO2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
X
References
Muller S, et al., Nat Rev Mol Cell Biol. 2001 2(3):202-10 Review.|Hochstrasser M. Cell. 2001 107(1):5-8. Review.|Kahyo T, et al., Mol Cell. 2001 Sep;8(3):713-8.|Yeh ET, et al., Gene. 2000 May 2;248(1-2):1-14. Review.|Keane,M.M., et al., Oncogene 18 (22), 3365-3375 (1999)