TRAP100 Antibody
Cat# MBS8582672-0,1mL-Biotin
Size : 0.1mL(Biotin)
Brand : MyBiosource
Contact local distributor :
Phone : +1 850 650 7790
TRAP100 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582672MBS8582672 is an antibody targeting TRAP100. Also known as TRAP100 Antibody. Reactive in Human, Rat, Bovine, Chicken, Pig. Host: Rabbit. Rabbit polyclonal antibody to TRAP100 More details
Product Overview
Online Datasheet in PDFProduct Name
TRAP100, Polyclonal Antibody
Full Product Name
TRAP100 Antibody
Product Gene Name
anti-TRAP100 antibody
Product Synonym Gene Name
MED24
Product Synonym Names
ARC100; CRSP4; DRIP100; KIAA0130; THRAP4; TRAP100; Mediator of RNA polymerase II transcription subunit 24; Activator-recruited cofactor 100 kDa component; ARC100; Cofactor required for Sp1 transcriptional activation subunit 4; CRSP complex subunit 4; Mediator complex subunit 24; Thyroid hormone receptor-associated protein 4; Thyroid hormone receptor-associated protein complex 100 kDa component; Trap100; hTRAP100; Vitamin D3 receptor-interacting protein complex 100 kDa component; DRIP100
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat, Bovine, Chicken, Pig
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of TRAP100 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
110,305 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (38175350..38210889, complement). Location: 17q21.1
OMIM
607000
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TRAP100. The exact sequence is proprietary.
Product Categories/Family for anti-TRAP100 antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TRAP100 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-TRAP100 antibody
WB: 1:500-1:1000
IHC: 1:50-1:200
IHC: 1:50-1:200
Other Notes
Small volumes of anti-TRAP100 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for TRAP100. It may not necessarily be applicable to this product.
NCBI Official Full Name
mediator of RNA polymerase II transcription subunit 24 isoform 2
NCBI Official Synonym Full Names
mediator complex subunit 24
NCBI Official Symbol
MED24
NCBI Official Synonym Symbols
CRSP4; ARC100; THRAP4; CRSP100; DRIP100; TRAP100
UniProt Protein Name
Mediator of RNA polymerase II transcription subunit 24
UniProt Synonym Protein Names
Activator-recruited cofactor 100 kDa component; ARC100; Cofactor required for Sp1 transcriptional activation subunit 4; CRSP complex subunit 4; Mediator complex subunit 24; Thyroid hormone receptor-associated protein 4; Thyroid hormone receptor-associated protein complex 100 kDa component; Trap100; hTRAP100; Vitamin D3 receptor-interacting protein complex 100 kDa component
Protein Family
Mediator of RNA polymerase II transcription
UniProt Gene Name
MED24
UniProt Synonym Gene Names
ARC100; CRSP4; DRIP100; KIAA0130; THRAP4; TRAP100; ARC100; CRSP complex subunit 4; Trap100; hTRAP100; DRIP100
UniProt Entry Name
MED24_HUMAN
NCBI Protein Information
mediator of RNA polymerase II transcription subunit 24; CRSP complex subunit 4; thyroid hormone receptor associated protein 4; thyroid hormone receptor-associated protein 4; activator-recruited cofactor 100 kDa component; cofactor required for Sp1 transcr
NCBI Summary for TRAP100
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for TRAP100
Trap100: a transcriptional coactivator protein of the thyroid hormone receptor-associated protein (TRAP) family. Forms a complex with the thyroid hormone receptor (TR) and markedly enhance TR-mediated transcription in vitro. Interacts and co-precipitates with Trap220 but does not directly bind nuclear hormone receptors.
Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 17q21.1
Cellular Component: nucleoplasm; Srb-mediator complex; nucleus
Molecular Function: protein binding; histone acetyltransferase activity; ligand-dependent nuclear receptor transcription coactivator activity; vitamin D receptor binding; transcription cofactor activity; thyroid hormone receptor binding; receptor activity
Biological Process: regulation of transcription from RNA polymerase II promoter; steroid hormone receptor signaling pathway; transcription initiation from RNA polymerase II promoter; protein heterooligomerization; positive regulation of transcription, DNA-dependent; androgen receptor signaling pathway; stem cell maintenance; gene expression; histone acetylation
Show more Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 17q21.1
Cellular Component: nucleoplasm; Srb-mediator complex; nucleus
Molecular Function: protein binding; histone acetyltransferase activity; ligand-dependent nuclear receptor transcription coactivator activity; vitamin D receptor binding; transcription cofactor activity; thyroid hormone receptor binding; receptor activity
Biological Process: regulation of transcription from RNA polymerase II promoter; steroid hormone receptor signaling pathway; transcription initiation from RNA polymerase II promoter; protein heterooligomerization; positive regulation of transcription, DNA-dependent; androgen receptor signaling pathway; stem cell maintenance; gene expression; histone acetylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-TRAP100 antibody
| Reference Product | PubMed Publications |
|---|---|
| PPARG antibody | >1 publications with TRAP100 and PPARG |
Pathways associated with anti-TRAP100 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Developmental Biology Pathway antibodies | Developmental Biology Pathway Diagram |
| Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies | Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram |
| Gene Expression Pathway antibodies | Gene Expression Pathway Diagram |
| Generic Transcription Pathway antibodies | Generic Transcription Pathway Diagram |
| Metabolism Pathway antibodies | Metabolism Pathway Diagram |
| Metabolism Of Lipids And Lipoproteins Pathway antibodies | Metabolism Of Lipids And Lipoproteins Pathway Diagram |
| PPARA Activates Gene Expression Pathway antibodies | PPARA Activates Gene Expression Pathway Diagram |
| Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies | Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram |
| Transcriptional Regulation Of White Adipocyte Differentiation Pathway antibodies | Transcriptional Regulation Of White Adipocyte Differentiation Pathway Diagram |
Diseases associated with anti-TRAP100 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Breast Neoplasms Antibodies | >3 publications with TRAP100 and Breast Neoplasms |
| Death Antibodies | >3 publications with TRAP100 and Death |
| Immune System Diseases Antibodies | >1 publications with TRAP100 and Immune System Diseases |
| Neoplasm Metastasis Antibodies | >1 publications with TRAP100 and Neoplasm Metastasis |
| Prostatic Diseases Antibodies | >1 publications with TRAP100 and Prostatic Diseases |
| Mammary Neoplasms, Animal Antibodies | >1 publications with TRAP100 and Mammary Neoplasms, Animal |
Organs/Tissues associated with anti-TRAP100 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Thyroid Antibodies | >3 publications with TRAP100 and Thyroid |
| Salivary Gland Antibodies | >2 publications with TRAP100 and Salivary Gland |
| Mouth Antibodies | >2 publications with TRAP100 and Mouth |
| Blood Antibodies | >1 publications with TRAP100 and Blood |
| Eye Antibodies | >1 publications with TRAP100 and Eye |
| Kidney Antibodies | >1 publications with TRAP100 and Kidney |
| Prostate Antibodies | >1 publications with TRAP100 and Prostate |
| Liver Antibodies | >1 publications with TRAP100 and Liver |
| Mammary Gland Antibodies | >1 publications with TRAP100 and Mammary Gland |
| Embryonic Tissue Antibodies | >1 publications with TRAP100 and Embryonic Tissue |