Discover a breakthrough in tissue fixation with Glyoxal Acid-Free (GAF) fixative, a non-toxic, non-carcinogenic alternative to formalin. Join our webinar to explore how Addax Biosciences’ patented innovation revolutionizes pathology with superior morphological and molecular preservation.
Discover the Future of Tissue Fixation
Unveil Glyoxal Acid-Free (GAF) fixative, a non-toxic, non-carcinogenic innovation that surpasses formalin in histological and molecular diagnostics. Join leading experts to explore its clinical validation and transformative potential in pathology.
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Webinar Overview
For over a century, formalin has been the gold standard for histological fixation, preserving tissue morphology effectively. Yet, its toxicity, carcinogenicity, and poor nucleic acid preservation in formalin-fixed paraffin-embedded (FFPE) tissues are critical drawbacks.
Enter GAF fixative, a patented breakthrough by Addax Biosciences. GAF delivers superior structural and molecular preservation without the health risks of formalin, paving the way for safer, more effective diagnostics.
An open-label, non-inferiority, multicentric trial was performed comparing fixation of histological specimens with GAF fixative vs standard phosphate-buffered formalin (PBF), evaluating the morphological and immunophenotypic preservation and the diagnostic value. The results proved the non-inferiority of GAF as compared to PBF for all organs tested (breast, colon, lung, endometrium, and prostate cancers) and highlight the capability of GAF to ensure both structural preservation and diagnostic value of the preparations.
- Morphology: GAF matches PBF in tissue structure preservation.
- Immunophenotyping: Comparable diagnostic accuracy for immunohistochemistry.
- Diagnostic Value: GAF equals or surpasses PBF performance.
Meet Our Speakers
Professor Emeritus of Pathological Anatomy, University of Turin, and member of the Italian National Academy (Accademia dei Lincei). An internationally renowned expert in molecular analysis of cells and tissues, he has authored numerous articles and patents in diagnostic pathology.
Past Roles:
- Full Professor of Pathological Anatomy and Histology, University of Turin.
- Dean of the Specialized Degree in Technical and Diagnostic Sciences.
- Head of Unit III of Diagnostic Pathology, S. Giovanni Battista Hospital, Turin.
Researcher at IRCCS, Candiolo, specializing in molecular biology applied to oncology. His expertise includes NGS, Sanger sequencing, RNA-seq, and epigenetic analysis, with numerous publications in precision medicine and cancer genomics.
GAF represents a paradigm shift, offering:
Safer Work Environments: Non-toxic and non-carcinogenic.
Enhanced Diagnostics: Supports genomic and transcriptomic analyses.
Sustainability: Environmentally friendly alternative to formalin.
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