4-Butylresorcinol [18979-61-8]
Cat# T7125-500mg
Size : 500mg
Brand : TargetMol
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4-Butylresorcinol
(Synonyms: Butylresorcinol) Copy Product Info
4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
Cas No. 18979-61-8
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.48%
Appearance:Solid
Color:White
COA LCMS HNMR
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent. |
| Targets & IC50 | Tyrosinase:11.27 μM |
| In vitro | 4-Butylresorcinol (4-n-butylresorcinol) significantly inhibits melanin synthesis in a concentration-dependent manner. It is also found to inhibit the activity of tyrosinase, the rate-limiting melanogenic enzyme. 4-Butylresorcinol does not induce ERK, Akt activation, or MITF degradation, and has no effect on cAMP response element binding protein (CREB) phosphorylation, which stimulates MITF expression. |
| Synonyms | Butylresorcinol |
| Molecular Weight | 166.22 |
| Formula | C10H14O2 |
| Cas No. | 18979-61-8 |
| Smiles | CCCCc1ccc(O)cc1O |
| Relative Density. | Ca. 1.04 g/cm3. Temperature:25 °C. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (1504.03 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+90% Saline: 10 mg/mL (60.16 mM), Solution. 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (24.06 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||