Acetyl-PHF6 amide (TFA)
Cat# HY-P1675A-5mg
Size : 5mg
Brand : MedChemExpress
Acetyl-PHF6 amide TFA (AcPHF6 TFA) is a tau derived hexapeptide.
For research use only. We do not sell to patients.
Custom Peptide Synthesis
Acetyl-PHF6 amide TFA Chemical Structure
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Description |
Acetyl-PHF6 amide TFA (AcPHF6 TFA) is a tau derived hexapeptide. |
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Molecular Weight |
903.99 |
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Formula |
C40H64F3N9O11 |
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Unlabeled CAS |
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Appearance |
Solid |
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Color |
White to off-white |
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Sequence |
Ac-Val-Gln-Ile-Val-Tyr-Lys-NH2 |
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Sequence Shortening |
Ac-VQIVYK-NH2 |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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Solvent & Solubility |
In Vitro:
DMSO : 67.5 mg/mL (74.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO
+
%
+
%
Tween-80
+
%
Saline
The co-solvents required include: DMSO,
. All of co-solvents are available by MedChemExpress (MCE).
, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration:
mg/mL
Method for preparing stock solution:
mg
drug dissolved in
μL
DMSO (Stock solution concentration: mg/mL).
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take
μL DMSO stock solution, add
μL .
μL , mix evenly, next add
μL Tween 80, mix evenly, then add
μL Saline.
If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
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Purity & Documentation | |||||||||||||
References |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO | 1 mM | 1.1062 mL | 5.5310 mL | 11.0621 mL | 27.6552 mL |
5 mM | 0.2212 mL | 1.1062 mL | 2.2124 mL | 5.5310 mL | |
10 mM | 0.1106 mL | 0.5531 mL | 1.1062 mL | 2.7655 mL | |
15 mM | 0.0737 mL | 0.3687 mL | 0.7375 mL | 1.8437 mL | |
20 mM | 0.0553 mL | 0.2766 mL | 0.5531 mL | 1.3828 mL | |
25 mM | 0.0442 mL | 0.2212 mL | 0.4425 mL | 1.1062 mL | |
30 mM | 0.0369 mL | 0.1844 mL | 0.3687 mL | 0.9218 mL | |
40 mM | 0.0277 mL | 0.1383 mL | 0.2766 mL | 0.6914 mL | |
50 mM | 0.0221 mL | 0.1106 mL | 0.2212 mL | 0.5531 mL | |
60 mM | 0.0184 mL | 0.0922 mL | 0.1844 mL | 0.4609 mL |
Acetyl-PHF6 amide TFA Related Classifications
- Neuronal Signaling
- Tau Protein