ADHP [119171-73-2]
Cat# T18912-5mg
Size : 5mg
Brand : TargetMol
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ADHP (Synonyms: 10-Acetyl-3,7-dihydroxyphenoxazine)
ADHP
Copy Product InfoSynonyms 10-Acetyl-3,7-dihydroxyphenoxazine
Cas No. 119171-73-2
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.57%
Appearance:Solid
Color:White to Yellow
COA HNMR LCMS
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | ADHP (10-Acetyl-3,7-dihydroxyphenoxazine) is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm). |
| In vitro | To obtain the parameters Km and kcat for Compound I, two independent methods are used. Initially, the oxidation of ADHP using the injector functionality built-in to the fluorescence plate reader is studied. The auto-injector dispenses the H2O2 to initiate the reaction, as a means of generating a set of progress curves. Analysis for MPO-mediated oxidation of ADHP gives a Km of 31±4 μM and the kcat of 186± 6/s. The kobs also increase over the experimental range of ADHP concentrations from 1 to 80 μM and for the converse experiment holding substrate constant over 3 to 45 nM MPO. The apparent second-order rate constant obtain from the slope of kobs against ADHP concentration Kappon is 2.1±0.2 mM/s. |
| Synonyms | 10-Acetyl-3,7-dihydroxyphenoxazine |
| Molecular Weight | 257.24 |
| Formula | C14H11NO4 |
| Cas No. | 119171-73-2 |
| Smiles | OC1=CC=C2C(OC(C=C(O)C=C3)=C3N2C(C)=O)=C1 |
| Relative Density. | 1.459g/cm3 |
| Storage | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (233.25 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||