| Short Description : | Mouse monoclonal anti-Alpha-actinin-2 (C-Term) for use in WB and IF in Human, Rat, Cow, Chicken, Dog, Pig and Zebrafish samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF |
| Host: | Mouse |
| Reactivity: | Human/Rat/Cow/Chicken/Dog/Pig/Zebrafish |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:1000-1:2000IF 1:100-1:500 |
| Formulation: | Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
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| Immunogen: | Purified recombinant human Actinin-Alpha 2 (C-terminus) protein fragments expressed in E.coli. |
| Immunogen Region: | C-Term |
| Specificity: | Actinin-Alpha 2 Monoclonal Antibody detects endogenous levels of Actinin-Alpha 2 protein. |
| Post Translational Modifications | Ubiquitinated by FBXL22, leading to proteasomal degradation. |
| Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
| Protein Name | Alpha-Actinin-2Alpha-Actinin Skeletal Muscle Isoform 2F-Actin Cross-Linking Protein |
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| Cellular Localisation | CytoplasmMyofibrilSarcomereZ LineColocalizes With Myoz1 And Flnc At The Z-Lines Of Skeletal Muscle |
| Alternative Antibody Names | Anti-Alpha-Actinin-2 antibodyAnti-Alpha-Actinin Skeletal Muscle Isoform 2 antibodyAnti-F-Actin Cross-Linking Protein antibodyAnti-ACTN2 antibody |
Information sourced from Uniprot.org