Mouse anti-Human/Monkey CD19 Antibody
Product Description
Specifications
| Size | 20 µg, 100 µg |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P15391 |
| Gene Id | 930 |
| Gene Symbols | CD19 |
| Protein Name / Synonyms | B-lymphocyte antigen CD19 (B-lymphocyte surface antigen B4) (Differentiation antigen CD19) (T-cell surface antigen Leu-12) (CD antigen CD19) |
| Immunogen | Human CD19 recombinant protein was used as immunogen for this CD19 antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 0.2 mg/ml in 1X PBS (pH 7.4) with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | Flow Cytometry: 0.5-1ug/million cells Immunofluorescence: 0.5-1ug/ml,, |
| Domain / Region / Terminus | Cell surface |
| Research Area | Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
CD19 is expressed on follicular dendritic cells and B cells. It is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. [Wiki]
Storage
CD19 antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Expiration:
12 months from the date of shipment when stored properly.


