Mouse anti-Human CD31 Antibody [IHC only]
Anti-CD31 Antibody
Anti-CD31 Antibody
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Product Description
Specifications
| Size | 7 mL |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P16284 |
| Gene Id | 5175 |
| Gene Symbols | PECAM1 |
| Protein Name / Synonyms | Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31) |
| Preparation | Recombinant human protein |
| Isotype | Kappa, IgG1 |
| Purity | Protein G |
| Concentration (lot specific) | Prediluted in 1X PBS (pH 7.4) with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only* |
| Recommended Applications | Prediluted format : incubate for 30 min at RT (2) |
| Domain / Region / Terminus | Cell surface and cytoplasmic |
| Research Area | Angiogenesis, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
CD31, also called PECAM-1, is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. It is expressed by stem cells of the hematopoietic system and CD31 antibody can be used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. CD31 antibody has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. This antibody reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high expression level may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Storage
Store the CD31 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.