APC-Cy7 Linked Polyclonal Antibody to Carcinoembryonic Antigen (CEA)
Cat# MBS2116765-0,2mL
Size : 0.2mL
Brand : MyBiosource
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Carcinoembryonic Antigen (CEA) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2116765SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2116765 is an antibody targeting CEA. Also known as APC-Cy7 Linked Polyclonal Antibody to Carcinoembryonic Antigen (CEA). Reactive in Human, Rat. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Carcinoembryonic Antigen (CEA), Polyclonal Antibody
Full Product Name
APC-Cy7 Linked Polyclonal Antibody to Carcinoembryonic Antigen (CEA)
Product Gene Name
anti-CEA antibody
Product Synonym Names
CD66E; CD66; CEACAM5; Carcinoembryonic Antigen-related Cell Adhesion Molecule 5; Carcinoembryonic Antigen
Immunogen Sequence
Asp209~Leu 408
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against CEA. It has been selected for its ability to recognize CEA in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: CEA (MBS2111809)
APC-CY7 Conjugated Antibody: CEA (MBS2116765)
APC-CY7 Conjugated Antibody: CEA (MBS2116765)
Matching Pairs
APC-CY7 Conjugated Antibody: CEA (MBS2116765)
Immunogen: CEA (MBS2097543)
Immunogen: CEA (MBS2097543)
Molecular Weight
57,264 Da
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen Sequence
Asp209~Leu408
Cross Reactivity
Rat
Conjugation
APC-Cy7
Product Categories/Family for anti-CEA antibody
Tumor Immunity; Gastroenterology
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CEA antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Other Notes
Small volumes of anti-CEA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CEA. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
carcinoembryonic antigen-related cell adhesion molecule 1 isoform 1
NCBI Official Synonym Full Names
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
NCBI Official Symbol
Ceacam1
NCBI Official Synonym Symbols
Bgp; BGPR; CD66a; Ccam1
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 1
UniProt Synonym Protein Names
ATP-dependent taurocolate-carrier protein; Cell-CAM 105; C-CAM 105; Ecto-ATPase; GP110; pp120; CD_antigen: CD66a
Protein Family
Colicin
UniProt Gene Name
Ceacam1
UniProt Synonym Gene Names
C-CAM 105
UniProt Entry Name
CEAM1_RAT
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 1; GP110; pp120; C-CAM 105; ecto-ATPase; osteocalcin; cell-CAM 105; pp120/ecto-ATPase; ATP-dependent taurocolate-carrier protein; bone gamma-carboxyglutamic acid (Gla) protein; CEA-related cell adhes
NCBI Summary for CEA
glycoprotein component of bile; plays a role in cell adhesion [RGD, Feb 2006]
UniProt Comments for CEA
CEACAM1: carcinoembryonic antigen-related cell adhesion molecule 1. A cell-cell adhesion molecule that directly associates with annexin II. Has tumor suppressor activity in prostate carcinoma. Belongs to the immunoglobulin superfamily and the CEA family. Abundantly expressed in epithelia, vessel endothelia, trophoblasts, platelets and neutrophilic granulocytes. Also present in many cell types of the immune system such as B cells, T cells, NK cells, macrophages and dendritic cells. Five alternatively spliced isoforms have been described. Two isoforms are type I membrane proteins, while three are secreted.
Protein type: Membrane protein, integral; Immunoglobulin superfamily; Cell adhesion; Motility/polarity/chemotaxis
Cellular Component: extracellular space; membrane; integral to plasma membrane; brush border membrane; integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: viral receptor activity; protein homodimerization activity; virion binding; protein kinase binding
Biological Process: Peyer's patch development; negative regulation of JNK cascade; entry of virus into host cell; positive regulation of NFAT protein import into nucleus; positive regulation of JNK cascade; positive regulation of immunoglobulin secretion; signal transduction; calcium-independent cell-cell adhesion; negative regulation of interleukin-2 production; positive regulation of MAP kinase activity; negative regulation of T cell proliferation; negative regulation of cytokine production; calcium-dependent cell-cell adhesion; positive regulation of T cell proliferation; homophilic cell adhesion; cell adhesion
Show more Protein type: Membrane protein, integral; Immunoglobulin superfamily; Cell adhesion; Motility/polarity/chemotaxis
Cellular Component: extracellular space; membrane; integral to plasma membrane; brush border membrane; integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: viral receptor activity; protein homodimerization activity; virion binding; protein kinase binding
Biological Process: Peyer's patch development; negative regulation of JNK cascade; entry of virus into host cell; positive regulation of NFAT protein import into nucleus; positive regulation of JNK cascade; positive regulation of immunoglobulin secretion; signal transduction; calcium-independent cell-cell adhesion; negative regulation of interleukin-2 production; positive regulation of MAP kinase activity; negative regulation of T cell proliferation; negative regulation of cytokine production; calcium-dependent cell-cell adhesion; positive regulation of T cell proliferation; homophilic cell adhesion; cell adhesion
Research Articles on CEA
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-CEA antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| EGFR1 Signaling Pathway antibodies | EGFR1 Signaling Pathway Diagram |
Diseases associated with anti-CEA antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >215 publications with CEA and Neoplasms |
| Hepatitis Antibodies | >71 publications with CEA and Hepatitis |
| Gastrointestinal Diseases Antibodies | >61 publications with CEA and Gastrointestinal Diseases |
| Adenocarcinoma Antibodies | >48 publications with CEA and Adenocarcinoma |
| Liver Diseases Antibodies | >37 publications with CEA and Liver Diseases |
| Liver Neoplasms Antibodies | >31 publications with CEA and Liver Neoplasms |
| Breast Neoplasms Antibodies | >28 publications with CEA and Breast Neoplasms |
| Inflammation Antibodies | >27 publications with CEA and Inflammation |
| Lung Neoplasms Antibodies | >26 publications with CEA and Lung Neoplasms |
| Neoplasm Metastasis Antibodies | >23 publications with CEA and Neoplasm Metastasis |
Organs/Tissues associated with anti-CEA antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Liver Antibodies | >109 publications with CEA and Liver |
| Colon Antibodies | >61 publications with CEA and Colon |
| Lung Antibodies | >42 publications with CEA and Lung |
| Prostate Antibodies | >42 publications with CEA and Prostate |
| Kidney Antibodies | >38 publications with CEA and Kidney |
| Embryonic Tissue Antibodies | >21 publications with CEA and Embryonic Tissue |
| Brain Antibodies | >20 publications with CEA and Brain |
| Small Intestine Antibodies | >10 publications with CEA and Small Intestine |
| Pancreas Antibodies | >10 publications with CEA and Pancreas |
| Artery Antibodies | >7 publications with CEA and Artery |