APC-Cy7 Linked Polyclonal Antibody to Phospholipase A2 Activating Protein (PLAP)

Cat# MBS2116546-1mL

Size : 1mL

Brand : MyBiosource

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Phospholipase A2 Activating Protein (PLAP) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2116546
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MBS2116546 is an antibody targeting PLAP. Also known as APC-Cy7 Linked Polyclonal Antibody to Phospholipase A2 Activating Protein (PLAP). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Phospholipase A2 Activating Protein (PLAP), Polyclonal Antibody
Full Product Name
APC-Cy7 Linked Polyclonal Antibody to Phospholipase A2 Activating Protein (PLAP)
Product Gene Name
anti-PLAP antibody
Product Synonym Names
PLAA; PLA2P; PLA2-P; DOA1
Immunogen Sequence
Tyr534~Leu 792
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against PLAA. It has been selected for its ability to recognize PLAA in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: PLAA (MBS2028494)
APC-CY7 Conjugated Antibody: PLAP (MBS2116546)
Matching Pairs
APC-CY7 Conjugated Antibody: PLAP (MBS2116546)
Immunogen: PLAA (MBS2011090)
Molecular Weight
795
OMIM
603873
3D Structure
ModBase 3D Structure for Q9Y263
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen Sequence
Tyr534~Leu792
Cross Reactivity
Human
Conjugation
APC-Cy7

Product Categories/Family for anti-PLAP antibody

Enzyme & Kinase; Metabolic Pathway; Infection Immunity
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PLAP antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-PLAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PLAP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Phospholipase A-2-activating protein
NCBI Official Synonym Full Names
phospholipase A2-activating protein
NCBI Official Symbol
PLAA
NCBI Official Synonym Symbols
DOA1; PLAP; PLA2P
UniProt Protein Name
Phospholipase A-2-activating protein
Protein Family
Low-affinity putrescine importer
UniProt Gene Name
PLAA
UniProt Synonym Gene Names
PLAP; PLA2P; PLAP
UniProt Entry Name
PLAP_HUMAN
NCBI Protein Information
phospholipase A-2-activating protein; DOA1 homolog; phospholipase A2 activating protein

UniProt Comments for PLAP

PLAA: phospholipase A2 activating protein. A regulator of the production of eicosanoids and prostaglandin E(2) in immune and inflammatory responses. Belongs to the WD repeat PLAP family.

Protein type: Activator

Chromosomal Location of Human Ortholog: 9p21

Molecular Function: phospholipase A2 activator activity; protein binding

Biological Process: positive regulation of catalytic activity; phospholipid metabolic process; signal transduction; inflammatory response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLAP antibody

 Reference Product  PubMed Publications
 VCP antibody  >3 publications with PLAP and VCP

Pathways associated with anti-PLAP antibody

 Products by Pathway  Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram

Diseases associated with anti-PLAP antibody

 Disease Name  Pubmed Publications
 Poisoning Antibodies  >61 publications with PLAP and Poisoning
 Drug-Induced Liver Injury Antibodies  >48 publications with PLAP and Drug-Induced Liver Injury
 Liver Diseases Antibodies  >47 publications with PLAP and Liver Diseases
 Nervous System Diseases Antibodies  >17 publications with PLAP and Nervous System Diseases
 Necrosis Antibodies  >13 publications with PLAP and Necrosis
 Neurotoxicity Syndromes Antibodies  >10 publications with PLAP and Neurotoxicity Syndromes
 Disease Models, Animal Antibodies  >8 publications with PLAP and Disease Models, Animal
 Kidney Diseases Antibodies  >8 publications with PLAP and Kidney Diseases
 Lung Diseases Antibodies  >5 publications with PLAP and Lung Diseases
 Inflammation Antibodies  >5 publications with PLAP and Inflammation

Organs/Tissues associated with anti-PLAP antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >145 publications with PLAP and Liver
 Blood Antibodies  >93 publications with PLAP and Blood
 Kidney Antibodies  >20 publications with PLAP and Kidney
 Brain Antibodies  >13 publications with PLAP and Brain
 Lung Antibodies  >12 publications with PLAP and Lung
 Vascular Antibodies  >9 publications with PLAP and Vascular
 Muscle Antibodies  >5 publications with PLAP and Muscle
 Bone Antibodies  >5 publications with PLAP and Bone
 Adipose Tissue Antibodies  >4 publications with PLAP and Adipose Tissue
 Connective Tissue Antibodies  >4 publications with PLAP and Connective Tissue