APC-Linked Monoclonal Antibody to Interleukin 6 (IL6)
Cat# MBS2119190-1mL
Size : 1mL
Brand : MyBiosource
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Phone : +1 850 650 7790
Interleukin 6 (IL6) Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2119190SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2119190 is an antibody targeting IL6. Also known as APC-Linked Monoclonal Antibody to Interleukin 6 (IL6). Reactive in Sheep. Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
Interleukin 6 (IL6), Monoclonal Antibody
Full Product Name
APC-Linked Monoclonal Antibody to Interleukin 6 (IL6)
Product Gene Name
anti-IL6 antibody
Product Synonym Names
MGI2-A; MGI2A; HGF; BSF2; HSF; IFNB2; B-Cell Stimulatory Factor-2; Hybridoma/Plasmacytoma Growth Factor; Hepatocyte Stimulating Factor; Cytotoxic T-Cell Differentiation Factor
Immunogen Sequence
Gly30~Lys2 08
Clonality
Monoclonal
Isotype
IgG2a Kappa
Clone Number
C6
Host
Mouse
Species Reactivity
Sheep
Form/Format
Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Protein A + Protein G Affinity Chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a mouse monoclonal antibody raised against IL6. It has been selected for its ability to recognize IL6 in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: IL6 Clone #C6 (MBS2111087)
APC Conjugated Antibody: IL6 Clone #C6 (MBS2119190)
APC Conjugated Antibody: IL6 Clone #C6 (MBS2119190)
Matching Pairs
APC Conjugated Antibody: IL6 Clone #C6 (MBS2119190)
Immunogen: IL6 (MBS2009134)
Immunogen: IL6 (MBS2009134)
Molecular Weight
23,446 Da
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen Sequence
Gly30~Lys208
Cross Reactivity
Sheep
Conjugation
APC
Product Categories/Family for anti-IL6 antibody
Cytokine; Tumor Immunity; Infection Immunity; Cardiovascular Biology
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IL6 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Other Notes
Small volumes of anti-IL6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for IL6. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-6
NCBI Official Symbol
IL6
UniProt Protein Name
Interleukin-6
Protein Family
Interleukin
UniProt Gene Name
IL6
UniProt Synonym Gene Names
IL-6
UniProt Entry Name
IL6_SHEEP
NCBI Protein Information
interleukin-6; IL-6
UniProt Comments for IL6
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation ().
Show more Research Articles on IL6
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-IL6 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| African Trypanosomiasis Pathway antibodies | African Trypanosomiasis Pathway Diagram |
| African Trypanosomiasis Pathway antibodies | African Trypanosomiasis Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Chagas Disease (American Trypanosomiasis) Pathway antibodies | Chagas Disease (American Trypanosomiasis) Pathway Diagram |
| Chagas Disease (American Trypanosomiasis) Pathway antibodies | Chagas Disease (American Trypanosomiasis) Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytosolic DNA-sensing Pathway antibodies | Cytosolic DNA-sensing Pathway Diagram |
| Cytosolic DNA-sensing Pathway antibodies | Cytosolic DNA-sensing Pathway Diagram |
Diseases associated with anti-IL6 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Inflammation Antibodies | >2394 publications with IL6 and Inflammation |
| Necrosis Antibodies | >1731 publications with IL6 and Necrosis |
| Autoimmune Diseases Antibodies | >452 publications with IL6 and Autoimmune Diseases |
| Obesity Antibodies | >298 publications with IL6 and Obesity |
| Skin Diseases Antibodies | >296 publications with IL6 and Skin Diseases |
| Arthritis, Rheumatoid Antibodies | >268 publications with IL6 and Arthritis, Rheumatoid |
| Atherosclerosis Antibodies | >244 publications with IL6 and Atherosclerosis |
| Myocardial Ischemia Antibodies | >230 publications with IL6 and Myocardial Ischemia |
| Ischemia Antibodies | >117 publications with IL6 and Ischemia |
| Diabetes Mellitus, Type 2 Antibodies | >111 publications with IL6 and Diabetes Mellitus, Type 2 |
Organs/Tissues associated with anti-IL6 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Bone Antibodies | >416 publications with IL6 and Bone |