APC-Linked Polyclonal Antibody to Caspase 3 (CASP3)

Cat# MBS2146883-0,2mL

Size : 0.2mL

Brand : MyBiosource

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Caspase 3 (CASP3) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2146883
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MBS2146883 is an antibody targeting CASP3. Also known as APC-Linked Polyclonal Antibody to Caspase 3 (CASP3). Reactive in Bovine. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Caspase 3 (CASP3), Polyclonal Antibody
Full Product Name
APC-Linked Polyclonal Antibody to Caspase 3 (CASP3)
Product Gene Name
anti-CASP3 antibody
Product Synonym Names
Caspase 3; CPP32; CPP32B; SCA1; Apoptain; Yama; Apoptosis-Related Cysteine Peptidase; Cysteinyl Aspartate Specific Proteinases 3; SREBP cleavage activity 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine
Form/Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
>=0.1mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)
Preparation and Storage
Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Stable for 12 months if correctly stored.
Matching Pairs
Antibody: CASP3 (MBS2146883)
Immunogen: CASP3 (MBS2105285)
Matching Pairs
Unconjugated Antibody: CASP3 (MBS2151622)
APC Conjugated Antibody: CASP3 (MBS2146883)
Molecular Weight
31,136 Da
Immunogen Sequence Positions
Ser29~Asp175
3D Structure
ModBase 3D Structure for Q08DY9
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
APC

Product Categories/Family for anti-CASP3 antibody

Polyclonal Antibodies (Primary Abs); Primary, APC-conjugated; Signal transduction
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CASP3 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-CASP3 antibody
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL

Other Notes

Small volumes of anti-CASP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CASP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
caspase-3
NCBI Official Symbol
CASP3
UniProt Protein Name
Caspase-3
Protein Family
Caspase
UniProt Gene Name
CASP3
UniProt Synonym Gene Names
CASP-3
NCBI Protein Information
caspase-3

UniProt Comments for CASP3

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CASP3 antibody

Diseases associated with anti-CASP3 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >6413 publications with CASP3 and Necrosis
 Nervous System Diseases Antibodies  >5034 publications with CASP3 and Nervous System Diseases
 Inflammation Antibodies  >3501 publications with CASP3 and Inflammation
 Reperfusion Injury Antibodies  >2247 publications with CASP3 and Reperfusion Injury
 Liver Diseases Antibodies  >2195 publications with CASP3 and Liver Diseases
 Brain Ischemia Antibodies  >1601 publications with CASP3 and Brain Ischemia
 Heart Diseases Antibodies  >1502 publications with CASP3 and Heart Diseases
 Breast Neoplasms Antibodies  >1401 publications with CASP3 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >1259 publications with CASP3 and Neoplasms, Experimental
 Kidney Diseases Antibodies  >853 publications with CASP3 and Kidney Diseases

Organs/Tissues associated with anti-CASP3 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7401 publications with CASP3 and Brain
 Intestine Antibodies  >877 publications with CASP3 and Intestine
 Pancreas Antibodies  >737 publications with CASP3 and Pancreas
 Uterus Antibodies  >221 publications with CASP3 and Uterus
 Pineal Gland Antibodies  >38 publications with CASP3 and Pineal Gland
 Uncharacterized Tissue Antibodies  >6 publications with CASP3 and Uncharacterized Tissue
 Rumen Antibodies  >4 publications with CASP3 and Rumen