BMP2 Antibody

Cat# MBS8582457-0,1mL-HRP

Size : 0.1mL(HRP)

Brand : MyBiosource

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BMP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582457

MBS8582457 is an antibody targeting BMP2. Also known as BMP2 Antibody. Reactive in Human, Mouse, Rat, Bovine, Chicken, Pig, Rabbit, Sheep, Zebrafish. Host: Rabbit. Rabbit polyclonal antibody to BMP2 More details

Product Overview

Online Datasheet in PDF
Product Name
BMP2, Polyclonal Antibody
Full Product Name
BMP2 Antibody
Product Gene Name
anti-BMP2 antibody
Product Synonym Names
BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Chicken, Pig, Rabbit, Sheep, Zebrafish
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of BMP2 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
OMIM
112261
3D Structure
ModBase 3D Structure for P12643
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BMP2. The exact sequence is proprietary.

Product Categories/Family for anti-BMP2 antibody

Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-BMP2 antibody
Western Blot (WB)
Application Notes for anti-BMP2 antibody
WB: 1:500-1:1000

Other Notes

Small volumes of anti-BMP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BMP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Bone morphogenetic protein 2
NCBI Official Synonym Full Names
bone morphogenetic protein 2
NCBI Official Symbol
BMP2
NCBI Official Synonym Symbols
BDA2; BMP2A
UniProt Protein Name
Bone morphogenetic protein 2
UniProt Synonym Protein Names
Bone morphogenetic protein 2A; BMP-2A
Protein Family
Bone morphogenetic protein
UniProt Gene Name
BMP2
UniProt Synonym Gene Names
BMP2A; BMP-2; BMP-2A
UniProt Entry Name
BMP2_HUMAN
NCBI Protein Information
bone morphogenetic protein 2; BMP-2A; bone morphogenetic protein 2A

NCBI Summary for BMP2

The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008]

UniProt Comments for BMP2

Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BMP2 antibody

 Reference Product  PubMed Publications
 BMPR2 antibody  >206 publications with BMP2 and BMPR2
 BMPR1A antibody  >179 publications with BMP2 and BMPR1A
 SMAD4 antibody  >95 publications with BMP2 and SMAD4
 BMPR1B antibody  >58 publications with BMP2 and BMPR1B
 SMAD7 antibody  >33 publications with BMP2 and SMAD7
 NOG antibody  >11 publications with BMP2 and NOG
 ACVR2B antibody  >9 publications with BMP2 and ACVR2B
 GREM2 antibody  >8 publications with BMP2 and GREM2
 CHRD antibody  >3 publications with BMP2 and CHRD
 SOSTDC1 antibody  >2 publications with BMP2 and SOSTDC1

Pathways associated with anti-BMP2 antibody

 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signalling And Regulation Pathway antibodies  BMP Signalling And Regulation Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram

Diseases associated with anti-BMP2 antibody

 Disease Name  Pubmed Publications
 Bone Diseases Antibodies  >567 publications with BMP2 and Bone Diseases
 Necrosis Antibodies  >112 publications with BMP2 and Necrosis
 Inflammation Antibodies  >93 publications with BMP2 and Inflammation
 Pain Antibodies  >46 publications with BMP2 and Pain
 Hypertrophy Antibodies  >45 publications with BMP2 and Hypertrophy
 Hypertension Antibodies  >44 publications with BMP2 and Hypertension
 Fibrosis Antibodies  >34 publications with BMP2 and Fibrosis
 Kidney Diseases Antibodies  >32 publications with BMP2 and Kidney Diseases
 Breast Neoplasms Antibodies  >32 publications with BMP2 and Breast Neoplasms
 Atherosclerosis Antibodies  >25 publications with BMP2 and Atherosclerosis

Organs/Tissues associated with anti-BMP2 antibody

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >4170 publications with BMP2 and Bone
 Connective Tissue Antibodies  >647 publications with BMP2 and Connective Tissue
 Embryonic Tissue Antibodies  >455 publications with BMP2 and Embryonic Tissue
 Heart Antibodies  >192 publications with BMP2 and Heart
 Brain Antibodies  >161 publications with BMP2 and Brain
 Kidney Antibodies  >94 publications with BMP2 and Kidney
 Lung Antibodies  >82 publications with BMP2 and Lung
 Liver Antibodies  >70 publications with BMP2 and Liver
 Eye Antibodies  >63 publications with BMP2 and Eye
 Uterus Antibodies  >29 publications with BMP2 and Uterus