CARD4 (NOD1) (NM_006092) Human 3' UTR Clone
CAT#: SC212581
3' UTR clone of nucleotide-binding oligomerization domain containing 1 (NOD1) for miRNA target validation
Product Images
Specifications
| Product Data | |
| Vector | pMirTarget |
| Species | Human |
| Transfection Reporter | RFP |
| Assay Reporter | Luciferase |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Symbol | NOD1 |
| Synonyms | CARD4; CLR7.1; NLRC1 |
| ACCN | NM_006092 |
| Insert Size | 1141 bp |
| Sequence Data | >SC212581 3’UTR clone of NM_006092 The sequence shown below is from the reference sequence of NM_006092. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAGATGAGAAGCGGATTATCTGTTTCTGAGAGGATGCTTTCCTGTTCATGGGGTTTTTGCCCTGGAGC CTCAGCAGCAAATGCCACTCTGGGCAGTCTTTTGTGTCAGTGTCTTAAAGGGGCCTGCGCAGGCGGGAC TATCAGGAGTCCACTGCCTCCATGATGCAAGCCAGCTTCCTGTGCAGAAGGTCTGGTCGGCAAACTCCC TAAGTACCCGCTACAATTCTGCAGAAAAAGAATGTGTCTTGCGAGCTGTTGTAGTTACAGTAAATACAC TGTGAAGAGACTTTATTGCCTATTATAATTATTTTTATCTGAAGCTAGAGGAATAAAGCTGTGAGCAAA CAGAGGAGGCCAGCCTCACCTCATTCCAACACCTGCCATAGGGACCAACGGGAGCGAGTTGGTCACCGC TCTTTTCATTGAAGAGTTGAGGATGTGGCACAAAGTTGGTGCCAAGCTTCTTGAATAAAACGTGTTTGA TGGATTAGTATTATACCTGAAATATTTTCTTCCTTCTCAGCACTTTCCCATGTATTGATACTGGTCCCA CTTCACAGCTGGAGACACCGGAGTATGTGCAGTGTGGGATTTGACTCCTCCAAGGTTTTGTGGAAAGTT AATGTCAAGGAAAGGATGCACCACGGGCTTTTAATTTTAATCCTGGAGTCTCACTGTCTGCTGGCAAAG ATAGAGAATGCCCTCAGCTCTTAGCTGGTCTAAGAATGACGATGCCTTCAAAATGCTGCTTCCACTCAG GGCTTCTCCTCTGCTAGGCTACCCTCCTCTAGAAGGCTGAGTACCATGGGCTACAGTGTCTGGCCTTGG GAAGAAGTGATTCTGTCCCTCCAAAGAAATAGGGCATGGCTTGCCCCTGTGGCCCTGGCATCCAAATGG CTGCTTTTGTCTCCCTTACCTCGTGAAGAGGGGAAGTCTCTTCCTGCCTCCCAAGCAGCTGAAGGGTGA CTAAACGGGCGCCAAGACTCAGGGGATCGGCTGGGAACTGGGCCAGCAGAGCATGTTGGACACCCCCCA CCATGGTGGGCTTGTGGTGGCTGCTCCATGAGGGTGGGGGTGATACTACTAGATCACTTGTCCTCTTGC CAGCTCATTTGTTAATAAAATACTGAAAACACTCTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
| Restriction Sites | SgfI-MluI |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
| Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
| Reference Data | |
| RefSeq | NM_006092.4 |
| Summary | This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recognition receptor (PRR) that binds bacterial peptidoglycans and initiates inflammation. This protein has also been implicated in the immune response to viral and parasitic infection. Major structural features of this protein include an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. Mutations in this gene are associated with asthma, inflammatory bowel disease, Behcet disease and sarcoidosis in human patients. [provided by RefSeq, Aug 2017] |
| Locus ID | 10392 |
| MW | 42.9 |
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