Cat Fibroblast Growth Factor 23 ELISA Kit
Cat# MBS047852-96
Size : 96-Strip-Wells
Brand : MyBiosource
Contact local distributor :
Phone : +1 850 650 7790
Fibroblast Growth Factor 23 (FGF-23) ELISA Kit for Cat
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS047852This cat FGF-23 ELISA kit is a sandwich immunoassay for the quantitative measurement of fibroblast growth factor 23 in serum and plasma, supporting phosphate metabolism and feline chronic kidney disease research. Background: This Quantitative Sandwich ELISA… More details
Product Overview
Product Name
Fibroblast Growth Factor 23 (FGF-23), ELISA Kit
Full Product Name
Cat Fibroblast Growth Factor 23 ELISA Kit
Product Gene Name
FGF-23 elisa kit
Species Reactivity
Cat
Assay Type
Quantitative Sandwich
Detection Range
31.2pg/ml-1000pg/ml
Sensitivity
5.0pg/ml
Preparation and Storage
Store all reagents at 2-8 degree C
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Molecular Weight
27,954 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (4477393..4488894, complement). Location: 12p13.3
OMIM
193100
Other Notes
Small volumes of FGF-23 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for FGF-23 purchase
MBS047852 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fibroblast Growth Factor 23 (FGF-23) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FGF-23. The ELISA analytical biochemical technique of the MBS047852 kit is based on FGF-23 antibody-FGF-23 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FGF-23 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FGF-23. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for FGF-23. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fibroblast growth factor 23
NCBI Official Synonym Full Names
fibroblast growth factor 23
NCBI Official Symbol
FGF23
NCBI Official Synonym Symbols
ADHR; FGFN; HYPF; HPDR2; PHPTC
UniProt Protein Name
Fibroblast growth factor 23
UniProt Synonym Protein Names
Phosphatonin; Tumor-derived hypophosphatemia-inducing factor
Protein Family
Fibroblast growth factor
UniProt Gene Name
FGF23
UniProt Synonym Gene Names
HYPF; FGF-23
UniProt Entry Name
FGF23_HUMAN
NCBI Protein Information
fibroblast growth factor 23; phosphatonin; tumor-derived hypophosphatemia inducing factor
NCBI Summary for FGF-23
This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]
Show more UniProt Comments for FGF-23
FGF23: Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL. Acts directly on the parathyroid to decrease PTH secretion. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR). ADHR is characterized by low serum phosphorus concentrations, rickets, osteomalacia, leg deformities, short stature, bone pain and dental abscesses. Defects in FGF23 are a cause of hyperphosphatemic familial tumoral calcinosis (HFTC). HFTC is a severe autosomal recessive metabolic disorder that manifests with hyperphosphatemia and massive calcium deposits in the skin and subcutaneous tissues. Belongs to the heparin-binding growth factors family.
Protein type: Secreted; Secreted, signal peptide; Cytokine
Chromosomal Location of Human Ortholog: 12p13.3
Cellular Component: extracellular space; extracellular region
Molecular Function: growth factor activity; type 1 fibroblast growth factor receptor binding
Biological Process: epidermal growth factor receptor signaling pathway; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; negative regulation of hormone secretion; phosphate metabolic process; negative regulation of bone mineralization; cellular phosphate ion homeostasis; insulin receptor signaling pathway; innate immune response; negative regulation of osteoblast differentiation; phosphate ion homeostasis; cell differentiation; vitamin D catabolic process
Disease: Hypophosphatemic Rickets, Autosomal Dominant
Show more Protein type: Secreted; Secreted, signal peptide; Cytokine
Chromosomal Location of Human Ortholog: 12p13.3
Cellular Component: extracellular space; extracellular region
Molecular Function: growth factor activity; type 1 fibroblast growth factor receptor binding
Biological Process: epidermal growth factor receptor signaling pathway; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; negative regulation of hormone secretion; phosphate metabolic process; negative regulation of bone mineralization; cellular phosphate ion homeostasis; insulin receptor signaling pathway; innate immune response; negative regulation of osteoblast differentiation; phosphate ion homeostasis; cell differentiation; vitamin D catabolic process
Disease: Hypophosphatemic Rickets, Autosomal Dominant
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with FGF-23 elisa kit
| Reference Product | PubMed Publications |
|---|---|
| PTH elisa kit | >202 publications with FGF-23 and PTH |
| PHEX elisa kit | >87 publications with FGF-23 and PHEX |
| FGFR1 elisa kit | >41 publications with FGF-23 and FGFR1 |
| GALNT3 elisa kit | >36 publications with FGF-23 and GALNT3 |
| MEPE elisa kit | >24 publications with FGF-23 and MEPE |
| FGFR3 elisa kit | >11 publications with FGF-23 and FGFR3 |
| FGFR2 elisa kit | >10 publications with FGF-23 and FGFR2 |
| FGFR4 elisa kit | >9 publications with FGF-23 and FGFR4 |
| FGF1 elisa kit | >5 publications with FGF-23 and FGF1 |
Pathways associated with FGF-23 elisa kit
| Products by Pathway | Pathway Diagram |
|---|---|
| Activated Point Mutants Of FGFR2 Pathway antibodies | Activated Point Mutants Of FGFR2 Pathway Diagram |
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies | Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram |
| DAP12 Interactions Pathway antibodies | DAP12 Interactions Pathway Diagram |
| DAP12 Signaling Pathway antibodies | DAP12 Signaling Pathway Diagram |
| Disease Pathway antibodies | Disease Pathway Diagram |
| Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies | Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram |
| Downstream Signal Transduction Pathway antibodies | Downstream Signal Transduction Pathway Diagram |
| Downstream Signaling Of Activated FGFR Pathway antibodies | Downstream Signaling Of Activated FGFR Pathway Diagram |
| FGF Signaling Pathway antibodies | FGF Signaling Pathway Diagram |
Diseases associated with FGF-23 elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Kidney Diseases Antibodies | >320 publications with FGF-23 and Kidney Diseases |
| Rickets Antibodies | >180 publications with FGF-23 and Rickets |
| Phosphorus Metabolism Disorders Antibodies | >168 publications with FGF-23 and Phosphorus Metabolism Disorders |
| Bone Diseases, Metabolic Antibodies | >166 publications with FGF-23 and Bone Diseases, Metabolic |
| Hyperphosphatemia Antibodies | >129 publications with FGF-23 and Hyperphosphatemia |
| Renal Insufficiency Antibodies | >124 publications with FGF-23 and Renal Insufficiency |
| Hyperparathyroidism, Secondary Antibodies | >86 publications with FGF-23 and Hyperparathyroidism, Secondary |
| Calcinosis Antibodies | >78 publications with FGF-23 and Calcinosis |
| Hypophosphatemic Rickets, Autosomal Dominant Antibodies | >63 publications with FGF-23 and Hypophosphatemic Rickets, Autosomal Dominant |
| Hypertension Antibodies | >54 publications with FGF-23 and Hypertension |
Organs/Tissues associated with FGF-23 elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Embryonic Tissue Antibodies | >8 publications with FGF-23 and Embryonic Tissue |
| Testis Antibodies | >1 publications with FGF-23 and Testis |
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