Catalase Microplate Assay Kit

Cat# MBS8243260-100

Size : 100Assays

Brand : MyBiosource

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Phone : +1 850 650 7790

Catalase (CAT) Assay Kit for General

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8243260

Background: Catalase is an antioxidant enzyme ubiquitously present in mammalian and non-mammalian aerobic cells containing a cytochrome system. It was initially isolated from ox liver and later from blood, bacterial, and plant sources. The enzyme contains 4… More details

Product Overview

Online Datasheet in PDF
Product Name
Catalase, Assay Kit
Full Product Name
Catalase Microplate Assay Kit
Product Gene Name
CAT assay kit
Product Synonym Names
EC 1.11.1.6; Catalase
Species Reactivity
General
Samples
Urine, Serum, Plasma, Tissue extracts, Cell lysate, Cell culture media and Other biological fluids Samples
Detection Range
0.5 mmol/L - 50 mmol/L
Preparation and Storage
Shipped and store at 4 degree C for 6 months.
Molecular Weight
59,756 Da
OMIM
115500
Applications Tested/Suitable for CAT assay kit
Functional Assay

Typical Testing Data/Standard Curve (for reference only) of CAT assay kit

General CAT Assay Kit – Cat# MBS8243260

Other Notes

Small volumes of CAT assay kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CAT purchase

MBS8243260 is an assay kit targeting CAT. Also known as Catalase Microplate Assay Kit. Reactive in General.

Additional Details

NCBI/Uniprot data below describe general gene information for CAT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
catalase
NCBI Official Synonym Full Names
catalase
NCBI Official Symbol
CAT
UniProt Protein Name
Catalase
Protein Family
Catalase
UniProt Gene Name
CAT
UniProt Entry Name
CATA_HUMAN
NCBI Protein Information
catalase

NCBI Summary for CAT

This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
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UniProt Comments for CAT

Catalase: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. Homotetramer. Belongs to the catalase family.

Protein type: Oxidoreductase; Mitochondrial; Amino Acid Metabolism - tryptophan; Hydrolase; EC 1.11.1.6; Energy Metabolism - methane; Endoplasmic reticulum; Apoptosis

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytosol; endoplasmic reticulum; extracellular space; focal adhesion; Golgi apparatus; intracellular membrane-bound organelle; lysosome; membrane; mitochondrial intermembrane space; mitochondrion; peroxisomal matrix; peroxisomal membrane; peroxisome; plasma membrane

Molecular Function: aminoacylase activity; antioxidant activity; catalase activity; enzyme binding; heme binding; metal ion binding; NADP binding; oxidoreductase activity, acting on peroxide as acceptor; protein homodimerization activity; receptor binding

Biological Process: activation of NF-kappaB transcription factor; aerobic respiration; aging; cholesterol metabolic process; hemoglobin metabolic process; hydrogen peroxide catabolic process; inhibition of NF-kappaB transcription factor; negative regulation of apoptosis; nucleobase, nucleoside and nucleotide metabolic process; osteoblast differentiation; positive regulation of cell division; positive regulation of phosphoinositide 3-kinase cascade; protein homotetramerization; protein tetramerization; purine base metabolic process; purine nucleotide catabolic process; response to activity; response to cadmium ion; response to drug; response to estradiol stimulus; response to ethanol; response to hydrogen peroxide; response to hyperoxia; response to hypoxia; response to inactivity; response to insulin stimulus; response to L-ascorbic acid; response to lead ion; response to light intensity; response to ozone; response to reactive oxygen species; response to vitamin A; response to vitamin E; triacylglycerol metabolic process; ureteric bud development; UV protection

Disease: Acatalasemia
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CAT assay kit

 Reference Product  PubMed Publications
 SOD1 assay kit  >312 publications with CAT and SOD1
 SOD2 assay kit  >236 publications with CAT and SOD2
 GSR assay kit  >57 publications with CAT and GSR
 SOD3 assay kit  >35 publications with CAT and SOD3
 AKT1 assay kit  >15 publications with CAT and AKT1
 FOXO3 assay kit  >12 publications with CAT and FOXO3
 XDH assay kit  >11 publications with CAT and XDH
 PEX5 assay kit  >1 publications with CAT and PEX5

Pathways associated with CAT assay kit

 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Folate Metabolism Pathway antibodies  Folate Metabolism Pathway Diagram
 FoxO Family Signaling Pathway antibodies  FoxO Family Signaling Pathway Diagram

Diseases associated with CAT assay kit

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1502 publications with CAT and Necrosis
 Asthma Antibodies  >1398 publications with CAT and Asthma
 Diabetes Mellitus Antibodies  >1343 publications with CAT and Diabetes Mellitus
 Hypertension Antibodies  >930 publications with CAT and Hypertension
 Edema Antibodies  >769 publications with CAT and Edema
 Seizures Antibodies  >734 publications with CAT and Seizures
 Disease Progression Antibodies  >696 publications with CAT and Disease Progression
 Brain Ischemia Antibodies  >584 publications with CAT and Brain Ischemia
 Heart Failure Antibodies  >558 publications with CAT and Heart Failure
 Reperfusion Injury Antibodies  >502 publications with CAT and Reperfusion Injury

Organs/Tissues associated with CAT assay kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >23775 publications with CAT and Brain
 Blood Antibodies  >17581 publications with CAT and Blood
 Nerve Antibodies  >10645 publications with CAT and Nerve
 Muscle Antibodies  >9949 publications with CAT and Muscle
 Eye Antibodies  >6046 publications with CAT and Eye
 Liver Antibodies  >5303 publications with CAT and Liver
 Heart Antibodies  >5163 publications with CAT and Heart
 Vascular Antibodies  >5160 publications with CAT and Vascular
 Skin Antibodies  >4490 publications with CAT and Skin
 Kidney Antibodies  >3557 publications with CAT and Kidney