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> CD222 (Insulin-Like Growth Factor II Receptor, IGF2R) (APC)

CD222 (Insulin-Like Growth Factor II Receptor, IGF2R) (APC)

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Cat# C2548-97B-APC-100ul

Size : 100ul

Brand : US Biological

Contact local distributor :


Phone : +1 850 650 7790

C2548-97B-APC CD222 (Insulin-Like Growth Factor II Receptor, IGF2R) (APC)

Clone Type
Monoclonal
Host
mouse
Source
human
Swiss Prot
P11717
Isotype
IgG1
Grade
Affinity Purified
Applications
FLISA
Crossreactivity
Hu Mk
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze

Applications:
Suitable for use in FLISA. Other applications not tested.

Recommended Dilution:
Optimal dilution to be determined by researcher.

Storage and Stability:
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.


Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG1|Clone No: MEM-238|Host: mouse|Source: human|Concentration: As Reported|Form: Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).|Purity: Purified by Protein A affinity chromatography.|Immunogen: Recombinant protein corresponding to vaccinia virus containing CD222|Specificity: Recognizes human CD222. Recognizes an epitope located in the region between extracellular domains 2 and 5, aa192-697, of CD222. Species Crossreactivity: non-human primates||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Recombinant protein corresponding to vaccinia virus containing CD222
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human CD222. Recognizes an epitope located in the region between extracellular domains 2 and 5, aa192-697, of CD222. Species Crossreactivity: non-human primates
References
1. Roberts, R.C. et al. (2010) Mistargeting of SH3TC2 away from the recycling endosome causes Charcot-Marie-Tooth disease type 4C. Hum Mol Genet. 19: 1009-18. 2. Adachi, A. et al. (2010) Golgi-associated GSK3beta regulates the sorting process of post-Golgi membrane trafficking. J Cell Sci. 123: 3215-25.3. Godar, S. et al. (2002) CD222 (Mannose-6 phosphate / insulin-like growth factor II-receptor) Summary and Workshop Report. In Leucocyte Typing VII: White Cell Differentiation Antigens. Edited by Mason, D. et al. Oxford University Press. pp482-485. 4. Rezgui, D. et al. (2009) Structure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growth. J Mol Endocrinol. 42: 341-56. 5. McCormick, P.J. et al. (2008) Palmitoylation controls recycling in lysosomal sorting and trafficking. Traffic. 9: 1984-97.