Reagents and instruments for immunology, cell biology and molecular biology.
 
> CD40 (PE)

CD40 (PE)

Print Print
Please log in

Cat# 214686-PE-100ul

Size : 100ul

Brand : US Biological

Contact local distributor :


Phone : +1 850 650 7790

214686-PECD40 (PE)

Specifications
Clone TypeMonoclonal
Hostmouse
Sourcebovine
Swiss ProtQ28203
IsotypeIgG1
GradeAffinity Purified
ApplicationsFC
CrossreactivityBo Sh
Shipping TempBlue Ice
Storage Temp4°C Do Not Freeze

CD40 cell surface antigen is expressed by B lymphocytes and a subset of T lymphocytes. CD40 plays an important role in the differentiation of B lymphocytes into effector cells, and is also involved in interactions between T and B lymphocytes.

Applications:
Suitable for use in Flow Cytometry and Functional Assays. Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Hybridoma:
X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice.

Storage and Stability:
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG1|Clone No: IL-A156|Host: mouse|Source: bovine|Concentration: As Reported|Form: Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).|Purity: Purified by Protein G affinity chromatography from tissue culture supernatant.|Specificity: Recognizes bovine CD40. Species Crossreactivity: sheep ||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
Purity
Purified by Protein G affinity chromatography from tissue culture supernatant.
Specificity
Recognizes bovine CD40. Species Crossreactivity: sheep
References
1. Langelaar, M.F. et al. (2005) Mycobacterium avium ssp. paratuberculosis recombinant heat shock protein 70interaction with different bovine antigen-presenting cells. Scand J Immunol. 61: 242-50. 2. Epardaud, M. et al. (2004) Enrichment for a CD26hi SIRP subset in lymph dendritic cells from the upper aero-digestive tract. J. Leukoc. Biol. 76: 553-561. 3. Glew, E.J. et al. (2003) Differential effects of bovine viral diarrhoea virus on monocytes and dendritic cells. J. Gen. Virol. 84: 1771-1780. 4. Norimatsu, M. et al. (2003) Differential response of bovine monocyte-derived macrophages and dendritic cells to infection with Salmonella typhimurium in a low-dose model in vitro. Immunology 108: 55- 61. 5. Haas, K.M. et al. (2001) Enhancing effects of anti-CD40 treatment on the immune response of SCID-bovine mice to Trypanosoma congolense infection. J Leukoc Biol. 70: 931-40.