CD5 Antibody
Cat# OAEE00903
Size : 100tests(T100)
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for CD5 Antibody |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | CRIS1 |
| Isotype | IgG2a |
| Host | Mouse |
| Conjugation | APC |
| Application | FC |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | stimulated human leukocytes |
| Purification | Purified by size-exclusion chromatography |
| Concentration | 10 ul / test |
| Specificity | The antibody CRIS1 reacts with the cell surface glycoprotein CD5, a 67kDa single-chain transmembrane glycoprotein expressed on mature T lymphocytes, most of thymocytes and B lymphocytes subset (B-1a lymphocytes). HLDA I; WS Code T 29 HLDA III; WS Code T 530 |
| Formulation | APC |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent. |
| Reference | Guarne A, Bravo J, Calvo J, Lozano F, Vives J, Fita I: Conformation of the hypervariable region L3 without the key proline residue. Protein Sci. 1996 Jan;5(1):167-9. Alberola-Ila J, Places L, Cantrell DA, Vives J, Lozano F: Intracellular events involved in CD5-induced human T cell activation and proliferation. J Immunol. 1992 Mar 1;148(5):1287-93. Arrizabalaga P, Mirapeix E, Darnell A, Torras A, Revert L: Cellular immunity analysis using monoclonal antibodies in human glomerulonephritis. Nephron. 1989;53(1):41-9. Leukocyte Typing III., McMichael A. J. et al. (Eds.), Oxford University Press (1987). Raman C: CD5, an important regulator of lymphocyte selection and immune tolerance. Immunol Res. 2002;26(1-3):255-63. Freedman AS, Freeman G, Whitman J, Segil J, Daley J, Levine H, Nadler LM: Expression and regulation of CD5 on in vitro activated human B cells. Eur J Immunol. 1989 May;19(5):849-55. |
|---|---|
| Gene Symbol | CD5 |
| Gene Full Name | CD5 molecule |
| Alias Symbols | CD5 antigen (p56-62), epididymis secretory sperm binding protein, LEU1, lymphocyte antigen T1/Leu-1, T-cell surface glycoprotein CD5, T1. |
| NCBI Gene Id | 921 |
| Protein Name | T-cell surface glycoprotein CD5 |
| Description of Target | May act as a receptor in regulating T-cell proliferation. |
| Uniprot ID | P06127 |
| Protein Accession # | NP_055022.2 |
| Nucleotide Accession # | NM_014207.3 |
