CD62L Antibody
Cat# MBS8582393-0,1mL-FITC
Size : 0.1mL(FITC)
Brand : MyBiosource
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Phone : +1 850 650 7790
CD62L Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582393MBS8582393 is an antibody targeting CD62L. Also known as CD62L Antibody. Reactive in Human, Mouse, Rat, Monkey. Host: Rabbit. Rabbit polyclonal antibody to CD62L More details
Product Overview
Online Datasheet in PDFProduct Name
CD62L, Polyclonal Antibody
Full Product Name
CD62L Antibody
Product Gene Name
anti-CD62L antibody
Product Synonym Gene Name
SELL
Product Synonym Names
LNHR; LYAM1; L-selectin; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; TQ1; gp90-MEL; CD62L
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Monkey
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of CD62L protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
42,187 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (169659806..169680843, complement). Location: 1q23-q25
OMIM
153240
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD62L. The exact sequence is proprietary.
Product Categories/Family for anti-CD62L antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CD62L antibody
Western Blot (WB)
Application Notes for anti-CD62L antibody
WB: 1:500-1:1000
Other Notes
Small volumes of anti-CD62L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CD62L. It may not necessarily be applicable to this product.
NCBI Official Full Name
L-selectin
NCBI Official Synonym Full Names
selectin L
NCBI Official Symbol
SELL
NCBI Official Synonym Symbols
TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1
UniProt Protein Name
L-selectin
UniProt Synonym Protein Names
CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; TQ1; gp90-MEL
Protein Family
L-selectin
UniProt Gene Name
SELL
UniProt Synonym Gene Names
LNHR; LYAM1; LAM-1; LECAM1
UniProt Entry Name
LYAM1_HUMAN
NCBI Protein Information
L-selectin; gp90-MEL; pln homing receptor; lymph node homing receptor; lymphocyte adhesion molecule 1; leukocyte surface antigen Leu-8; CD62 antigen-like family member L; leukocyte-endothelial cell adhesion molecule 1
NCBI Summary for CD62L
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Show more UniProt Comments for CD62L
SELL: Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. Belongs to the selectin/LECAM family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q23-q25
Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane
Molecular Function: heparin binding; protein binding; protease binding; cell adhesion molecule binding; carbohydrate binding; glycosphingolipid binding
Biological Process: regulation of immune response; cell adhesion; blood coagulation; leukocyte migration; response to ATP
Disease: Iga Nephropathy, Susceptibility To, 1
Show more Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q23-q25
Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane
Molecular Function: heparin binding; protein binding; protease binding; cell adhesion molecule binding; carbohydrate binding; glycosphingolipid binding
Biological Process: regulation of immune response; cell adhesion; blood coagulation; leukocyte migration; response to ATP
Disease: Iga Nephropathy, Susceptibility To, 1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-CD62L antibody
| Reference Product | PubMed Publications |
|---|---|
| CD34 antibody | >4 publications with CD62L and CD34 |
| CD44 antibody | >3 publications with CD62L and CD44 |
| MSN antibody | >1 publications with CD62L and MSN |
Pathways associated with anti-CD62L antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Cell Adhesion Molecules (CAMs) Pathway antibodies | Cell Adhesion Molecules (CAMs) Pathway Diagram |
| Cell Adhesion Molecules (CAMs) Pathway antibodies | Cell Adhesion Molecules (CAMs) Pathway Diagram |
| Cell Surface Interactions At The Vascular Wall Pathway antibodies | Cell Surface Interactions At The Vascular Wall Pathway Diagram |
| Hemostasis Pathway antibodies | Hemostasis Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies | Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram |
Diseases associated with anti-CD62L antibody
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >202 publications with CD62L and Nervous System Diseases |
| Liver Diseases Antibodies | >116 publications with CD62L and Liver Diseases |
| Inflammation Antibodies | >68 publications with CD62L and Inflammation |
| Pain Antibodies | >64 publications with CD62L and Pain |
| Heart Diseases Antibodies | >64 publications with CD62L and Heart Diseases |
| Gastrointestinal Diseases Antibodies | >59 publications with CD62L and Gastrointestinal Diseases |
| Necrosis Antibodies | >44 publications with CD62L and Necrosis |
| Kidney Diseases Antibodies | >35 publications with CD62L and Kidney Diseases |
| Fever Antibodies | >27 publications with CD62L and Fever |
| Hemorrhage Antibodies | >24 publications with CD62L and Hemorrhage |
Organs/Tissues associated with anti-CD62L antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >560 publications with CD62L and Blood |
| Liver Antibodies | >185 publications with CD62L and Liver |
| Bone Antibodies | >166 publications with CD62L and Bone |
| Muscle Antibodies | >128 publications with CD62L and Muscle |
| Heart Antibodies | >102 publications with CD62L and Heart |
| Kidney Antibodies | >94 publications with CD62L and Kidney |
| Brain Antibodies | >82 publications with CD62L and Brain |
| Vascular Antibodies | >81 publications with CD62L and Vascular |
| Spleen Antibodies | >73 publications with CD62L and Spleen |
| Lung Antibodies | >67 publications with CD62L and Lung |