Biovalley > CD7 Antibody
CD7 Antibody
Brand : Aviva Systems Biology
| Datasheets/Manuals | Printable datasheet for CD7 Antibody |
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| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | MEM-186 |
| Isotype | IgG1 |
| Host | Mouse |
| Conjugation | PerCP |
| Application | FC |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Human acute myelogenous leukaemia cell line KG-1. |
| Purification | Purified by size-exclusion chromatography |
| Concentration | 10 ul / test |
| Specificity | The MEM-186 antibody reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia. HLDA VI; WS Code T 6T-015 |
| Formulation | PerCP |
| Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent. |
| Reference | Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997). Nishimura M, Takanashi M, Okazaki H, Satake M, Nakajima K: Role of CD7 expressed in lung microvascular endothelial cells as Fc receptor for immunoglobulin M. Endothelium. 2006 Jul-Aug;13(4):287-92. Chang H, Yeung J, Brandwein J, Yi QL: CD7 expression predicts poor disease free survival and post-remission survival in patients with acute myeloid leukemia and normal karyotype. Leuk Res. 2007 Feb;31(2):157-62. Epub 2006 Jul 11. Lam GK, Liao HX, Xue Y, Alam SM, Scearce RM, Kaufman RE, Sempowski GD, Haynes BF. Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation byIFN-gamma. J Clin Immunol. 2005 Jan;25(1):41-9. Alaibac M, Pigozzi B, Belloni-Fortina A, Michelotto A, Saponeri A, Peserico A. CD7 expression in reactive and malignant human skin T-lymphocytes. Anticancer Res. 2003 May-Jun;23(3B):2707-10. |
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| Gene Symbol | CD7 |
| Gene Full Name | CD7 molecule |
| Alias Symbols | CD7 antigen (p41), GP40, LEU-9, p41 protein, T-cell antigen CD7, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41. |
| NCBI Gene Id | 924 |
| Protein Name | T-cell antigen CD7 |
| Description of Target | Not yet known. |
| Uniprot ID | P09564 |
| Protein Accession # | NP_006128.1 |
| Nucleotide Accession # | NM_006137.6 |
Protein interactions
| Name | # of Products |
|---|---|
| CTSL1 | 139 |
| LGALS1 | 190 |
| PI4K2A | 23 |
| PI4KA | 18 |
| PIK3R1 | 517 |
| SECTM1 | 12 |
| SNAP29 | 35 |
Biological pathways
| Name | # of Products |
|---|---|
| Immune response | 1416 |
| T cell activation | 158 |
| Transmembrane receptor protein tyrosine kinase signaling pathway | 153 |
Biological process
| Name | # of Products |
|---|---|
| Homeostasis of number of cells within a tissue | 17 |
| Immune response | 404 |
| T cell activation | 68 |
| Transmembrane receptor protein tyrosine kinase signaling pathway | 67 |
Cellular components
| Name | # of Products |
|---|---|
| Integral to membrane | 2793 |
| Membrane fraction | 437 |
| Plasma membrane | 2678 |
Protein function
| Name | # of Products |
|---|---|
| Receptor activity | 3624 |
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CD7 AntibodyCatalog #: OAEE00307Clone: MEM-186Application: FC|IHC-P|IP|WBFormat: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide -
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