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> Cx3cl1 Mouse shRNA Plasmid (Locus ID 20312)

Cx3cl1 Mouse shRNA Plasmid (Locus ID 20312)

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Cat# TR514650

Size : 1kit

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Cx3cl1 Mouse shRNA Plasmid (Locus ID 20312)

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SKU
TR514650
Cx3cl1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
 

Other products for "Cx3cl1 or NM_009142"

  • cDNA Clones
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  • Antibodies
Specifications
Product Data
Locus ID 20312
Synonyms AB030188; ABCD-3; AI848747; CX3C; Cxc3; D8Bwg0439e; Scyd1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Cx3cl1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 20312). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC006650, BC054838, NM_009142, NM_009142.1, NM_009142.2, NM_009142.3, BC013336, BC057891
UniProt ID O35188
Summary Acts as a ligand for both CX3CR1 and integrins. Binds to CX3CR1 and to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1 (By similarity). The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (PubMed:9177350, PubMed:10382755).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@biovalley.fr. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
Product Manuals
FAQs
  • shRNA (HuSH-29)
SDS
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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