FITC-Linked Polyclonal Antibody to Plasminogen Activator, Tissue (tPA)

Cat# MBS2043398-0,5mL

Size : 0.5mL

Brand : MyBiosource

Contact local distributor :


Phone : +1 850 650 7790

Plasminogen Activator (tPA) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2043398
SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2043398 is an antibody targeting tPA. Also known as FITC-Linked Polyclonal Antibody to Plasminogen Activator, Tissue (tPA). Reactive in Human, Mouse, Rat. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Plasminogen Activator (tPA), Polyclonal Antibody
Full Product Name
FITC-Linked Polyclonal Antibody to Plasminogen Activator, Tissue (tPA)
Product Gene Name
anti-tPA antibody
Product Synonym Names
PLAT; T-PA; t-plasminogen activator; Alteplase; Reteplase
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: tPA (MBS2006820)
FITC Conjugated Antibody: tPA (MBS2043398)
Matching Pairs
FITC Conjugated Antibody: tPA (MBS2043398)
Immunogen: tPA (MBS2009418)
Molecular Weight
44,373 Da
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
tPA (Ser36~Thr126)
Conjugation
FITC
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2006820
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-tPA antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-tPA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for tPA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
plasminogen activator
NCBI Official Synonym Full Names
plasminogen activator, tissue type
NCBI Official Symbol
PLAT
NCBI Official Synonym Symbols
TPA; T-PA
UniProt Protein Name
Tissue-type plasminogen activator
UniProt Synonym Protein Names
INN: Alteplase; INN: Reteplase
Protein Family
Taurine--pyruvate aminotransferase
UniProt Gene Name
PLAT
UniProt Synonym Gene Names
t-PA; t-plasminogen activator; tPA
NCBI Protein Information
tissue-type plasminogen activator

NCBI Summary for tPA

This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Show more

UniProt Comments for tPA

Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-tPA antibody

 Reference Product  PubMed Publications
 SERPINE1 antibody  >24 publications with tPA and SERPINE1
 PLG antibody  >8 publications with tPA and PLG
 HRG antibody  >1 publications with tPA and HRG
 ITGAM antibody  >1 publications with tPA and ITGAM
 SERPINF2 antibody  >1 publications with tPA and SERPINF2
 LRP1 antibody  >1 publications with tPA and LRP1

Pathways associated with anti-tPA antibody

 Products by Pathway  Pathway Diagram
 Blood Clotting Cascade Pathway antibodies  Blood Clotting Cascade Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Dissolution Of Fibrin Clot Pathway antibodies  Dissolution Of Fibrin Clot Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-tPA antibody

 Disease Name  Pubmed Publications
 Atherosclerosis Antibodies  >26 publications with tPA and Atherosclerosis
 Arterial Occlusive Diseases Antibodies  >25 publications with tPA and Arterial Occlusive Diseases
 Thrombosis Antibodies  >21 publications with tPA and Thrombosis
 Cerebral Infarction Antibodies  >20 publications with tPA and Cerebral Infarction
 Stroke Antibodies  >19 publications with tPA and Stroke
 Myocardial Infarction Antibodies  >15 publications with tPA and Myocardial Infarction
 Hypertension Antibodies  >14 publications with tPA and Hypertension
 Embolism and Thrombosis Antibodies  >12 publications with tPA and Embolism and Thrombosis
 Brain Ischemia Antibodies  >8 publications with tPA and Brain Ischemia
 Hemorrhage Antibodies  >7 publications with tPA and Hemorrhage

Organs/Tissues associated with anti-tPA antibody

 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >58 publications with tPA and Vascular
 Liver Antibodies  >52 publications with tPA and Liver
 Brain Antibodies  >47 publications with tPA and Brain
 Heart Antibodies  >42 publications with tPA and Heart
 Lung Antibodies  >35 publications with tPA and Lung
 Muscle Antibodies  >31 publications with tPA and Muscle
 Bone Antibodies  >21 publications with tPA and Bone
 Intestine Antibodies  >19 publications with tPA and Intestine
 Kidney Antibodies  >18 publications with tPA and Kidney
 Embryonic Tissue Antibodies  >16 publications with tPA and Embryonic Tissue