GH Protein
Cat# OPPA00467
Size : 100µg
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for OPPA00467 |
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| Predicted Species Reactivity | Human |
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| Product Format | Sterile Filtered White lyophilized (freeze-dried) powder. GH protein lyophilized from a 0.2um filtered concentrated solution with 20mM PB, pH 7.0 and 3% Mannitol. |
| Reconstitution and Storage | Reconstitution: It is recommended to reconstitute the lyophilized HGH in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Storage: Lyophilized GH although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution HGH should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Purity | Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
| Biological Activity | The ED50 was determined by the proliferation assay of rat lymphoma NB2-11 cells and was found to be less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 x 107 IU/mg. |
| Peptide Sequence | FPTIPLSRLF DNAMLRAHRL HQLAFDTYQE FEEAYIPKEQ KYSFLQNPQT SLCFSESIPT PSNREETQQK SNLELLRISL LLIQSWLEPV QFLRSVFANS LVYGASDSNV YDLLKDLEEG IQTLMGRLED GSPRTGQIFK QTYSKFDTNS HNDDALLKNY GLLYCFRKDM DKVETFLRIV QCRSVEGSCG F. |
| Source | E. coli |
| Gene Symbol | GH |
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| Alias Symbols | GH, GHN, GH-N, GHB5, IGHD2, hGH-N, IGHD1A, IGHD1B |
| NCBI Gene Id | 2688 |
| Protein Name | Somatotropin |
| Description of Target | GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. |
| Uniprot ID | P01241 |
| Protein Accession # | NP_000506.2 |
| Protein Size (# AA) | Recombinant |
