GLB1 Antibody

Cat# MBS856626-0,1mL-AF488

Size : 0.1mL(AF488)

Brand : MyBiosource

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GLB1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS856626

MBS856626 is an antibody targeting GLB1. Also known as GLB1 Antibody. Reactive in Human. More details

Product Overview

Online Datasheet in PDF
Product Name
GLB1, Antibody
Full Product Name
GLB1 Antibody
Product Gene Name
anti-GLB1 antibody
Product Synonym Names
Beta-galactosidase; EC=3.2.1.23; Acid beta-galactosidase; Lactase; Elastin receptor 1
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
GLB1 antibody detects endogenous levels of total GLB1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
72,751 Da
OMIM
230500
3D Structure
ModBase 3D Structure for P16278
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human GLB1.

Product Categories/Family for anti-GLB1 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GLB1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GLB1 antibody
WB: 1:500-1:1000
ELISA: 1:1000

Western Blot (WB) of anti-GLB1 antibody

Western blot analysis of extracts from 3T3 cells, using GLB1 antibody.
Anti-GLB1 Antibody – Cat# MBS856626

Product References and Citations for anti-GLB1 antibody

Oshima A., Biochem. Biophys. Res. Commun. 157:238-244(1988) [PubMed: 3143362]. Morreau H., J. Biol. Chem. 264:20655-20663(1989) [PubMed: 2511208]. Yamamoto Y., DNA Cell Biol. 9:119-127(1990) [PubMed: 2111707]. Morreau H., J. Biol. Chem. 264:20655-20663(1989) [PubMed: 2511208]. Yamamoto Y., DNA Cell Biol. 9:119-127(1990) [PubMed: 2111707].

Other Notes

Small volumes of anti-GLB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GLB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
beta-galactosidase isoform a preproprotein
NCBI Official Synonym Full Names
galactosidase beta 1
NCBI Official Symbol
GLB1
NCBI Official Synonym Symbols
EBP; ELNR1; MPS4B
UniProt Protein Name
Beta-galactosidase
UniProt Synonym Protein Names
Acid beta-galactosidase; Lactase; Elastin receptor 1
Protein Family
Beta-galactosidase
UniProt Gene Name
GLB1
UniProt Synonym Gene Names
ELNR1; Lactase
NCBI Protein Information
beta-galactosidase

NCBI Summary for GLB1

This gene encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene may result in GM1-gangliosidosis and Morquio B syndrome. [provided by RefSeq, Nov 2015]
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UniProt Comments for GLB1

Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GLB1 antibody

 Reference Product  PubMed Publications
 NEU1 antibody  >6 publications with GLB1 and NEU1
 CTSA antibody  >5 publications with GLB1 and CTSA

Pathways associated with anti-GLB1 antibody

 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Glycosaminoglycan Degradation Pathway antibodies  Glycosaminoglycan Degradation Pathway Diagram
 Glycosaminoglycan Degradation Pathway antibodies  Glycosaminoglycan Degradation Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Glycosphingolipid Biosynthesis - Ganglio Series Pathway antibodies  Glycosphingolipid Biosynthesis - Ganglio Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Ganglio Series Pathway antibodies  Glycosphingolipid Biosynthesis - Ganglio Series Pathway Diagram
 Glycosphingolipid Metabolism Pathway antibodies  Glycosphingolipid Metabolism Pathway Diagram
 HS-GAG Degradation Pathway antibodies  HS-GAG Degradation Pathway Diagram

Diseases associated with anti-GLB1 antibody

 Disease Name  Pubmed Publications
 Gangliosidosis, GM1 Antibodies  >42 publications with GLB1 and Gangliosidosis, GM1
 Mucopolysaccharidosis IV Antibodies  >12 publications with GLB1 and Mucopolysaccharidosis IV
 Neoplasms Antibodies  >6 publications with GLB1 and Neoplasms
 Disease Models, Animal Antibodies  >5 publications with GLB1 and Disease Models, Animal
 Kidney Diseases Antibodies  >2 publications with GLB1 and Kidney Diseases
 Adenocarcinoma Antibodies  >2 publications with GLB1 and Adenocarcinoma
 Inflammation Antibodies  >2 publications with GLB1 and Inflammation
 Drug Toxicity Antibodies  >2 publications with GLB1 and Drug Toxicity
 Precancerous Conditions Antibodies  >1 publications with GLB1 and Precancerous Conditions
 Cardiovascular Diseases Antibodies  >1 publications with GLB1 and Cardiovascular Diseases

Organs/Tissues associated with anti-GLB1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >10 publications with GLB1 and Blood
 Skin Antibodies  >8 publications with GLB1 and Skin
 Kidney Antibodies  >5 publications with GLB1 and Kidney
 Brain Antibodies  >4 publications with GLB1 and Brain
 Connective Tissue Antibodies  >3 publications with GLB1 and Connective Tissue
 Bone Antibodies  >3 publications with GLB1 and Bone
 Pancreas Antibodies  >3 publications with GLB1 and Pancreas
 Eye Antibodies  >3 publications with GLB1 and Eye
 Placenta Antibodies  >2 publications with GLB1 and Placenta
 Lung Antibodies  >2 publications with GLB1 and Lung