Goat Anti-Fumarase / FH Antibody
Cat# OAEB02064
Size : 100ug
Brand : Aviva Systems Biology
Contact local distributor :
Phone : +1 850 650 7790
Goat Anti-Fumarase / FH Antibody (OAEB02064)
| Datasheets/Manuals | Printable datasheet for Goat Anti-Fumarase / FH Antibody (OAEB02064) |
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| Predicted Species Reactivity | Dog|Human|Mouse|Rat |
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| Product Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Clonality | Polyclonal |
| Host | Goat |
| Application | ELISA|IHC|WB |
| Reconstitution and Storage | -20°C |
| Immunogen | Fumarase / FH |
| Purification | Ammonium Sulfate Precipitated; Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100% |
| Peptide Sequence | C-HPNDHVNKSQSSND |
| Concentration | 0.5 mg/ml |
| Purity | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Application Info | Peptide ELISA: antibody detection limit dilution 1:64000. Western Blot: Approx 48kDa band observed in Human Kidney, Liver and Lung lysates (calculated MW of 54.6kDa according to NP_000134.2). The observed molecular weight corresponds to earlier findings with antibodies from different sources. In transfected HEK293 transiently expressing Fumarase a band of approx. 55kDa is observed. This band is not observed in the non-transfected HEK293.Recommended concentration: 0.01-0.03ug/ml. |
| Reference | * Pollard PJ, Spencer-Dene B, Shukla D, Howarth K, Nye E, El-Bahrawy M, Deheragoda M, Joannou M, McDonald S, Martin A, Igarashi P, Varsani-Brown S, Rosewell I, Poulsom R, Maxwell P, Stamp GW, Tomlinson IP.; Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway.; Cancer Cell. 2007 Apr;11(4):311-9.; Pubmed 17418408 |
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| Gene Symbol | Fh|FH|Fh1 |
| Gene Full Name | fumarate hydratase|fumarate hydratase 1 |
| Alias Symbols | EF-3, epididymis secretory sperm binding protein, Fh, Fh-1, Fh1, FMRD, fuma, fumarase, fumarate hydratase 1, fumarate hydratase, mitochondrial, HLRCC, HsFH, LRCC, MCL, MCUL1. |
| NCBI Gene Id | 14194|2271|24368 |
| Protein Name | fumarate hydratase, mitochondrial [Homo sapiens] |
| Uniprot ID | P07954 |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_000134.2 |
| Molecular Weight | 54.6 |
