HRP-Linked Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5)

Cat# MBS2050045-0,5mL

Size : 0.5mL

Brand : MyBiosource

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Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2050045
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MBS2050045 is an antibody targeting SIGLEC5. Also known as HRP-Linked Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5). Reactive in Human, Pig. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5), Polyclonal Antibody
Full Product Name
HRP-Linked Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 5 (SIGLEC5)
Product Gene Name
anti-SIGLEC5 antibody
Product Synonym Names
CD170; CD33L2; OB-BP2; OBBP2; CD33 antigen-like 2; Obesity-binding protein 2; OB-binding protein 2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Pig
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: SIGLEC5 (MBS2001734)
HRP Conjugated Antibody: SIGLEC5 (MBS2050045)
Matching Pairs
HRP Conjugated Antibody: SIGLEC5 (MBS2050045)
Immunogen: SIGLEC5 (MBS2009961)
Molecular Weight
60,715 Da
OMIM
AF170484 mRNA
3D Structure
ModBase 3D Structure for O15389
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
SIGLEC5 (Phe458~Lys551)
Conjugation
HRP
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2001734
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-SIGLEC5 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-SIGLEC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SIGLEC5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sialic acid-binding Ig-like lectin 5
NCBI Official Synonym Full Names
sialic acid binding Ig like lectin 5
NCBI Official Symbol
SIGLEC5
NCBI Official Synonym Symbols
CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5
UniProt Protein Name
Sialic acid-binding Ig-like lectin 5
UniProt Synonym Protein Names
CD33 antigen-like 2; Obesity-binding protein 2; OB-BP2; OB-binding protein 2; CD_antigen: CD170
Protein Family
Sialic acid-binding Ig-like lectin
UniProt Gene Name
SIGLEC5
UniProt Synonym Gene Names
CD33L2; OBBP2; Siglec-5; OB-BP2; OB-binding protein 2
NCBI Protein Information
sialic acid-binding Ig-like lectin 5

NCBI Summary for SIGLEC5

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
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UniProt Comments for SIGLEC5

SIGLEC5: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.41

Molecular Function: protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SIGLEC5 antibody

 Reference Product  PubMed Publications
 CD24 antibody  >1 publications with SIGLEC5 and CD24
 TYROBP antibody  >1 publications with SIGLEC5 and TYROBP

Diseases associated with anti-SIGLEC5 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >16 publications with SIGLEC5 and Inflammation
 Asthma Antibodies  >10 publications with SIGLEC5 and Asthma
 Disease Models, Animal Antibodies  >7 publications with SIGLEC5 and Disease Models, Animal
 Respiratory Hypersensitivity Antibodies  >6 publications with SIGLEC5 and Respiratory Hypersensitivity
 Necrosis Antibodies  >4 publications with SIGLEC5 and Necrosis
 Fibrosis Antibodies  >3 publications with SIGLEC5 and Fibrosis
 Hypertension Antibodies  >1 publications with SIGLEC5 and Hypertension
 Birth Weight Antibodies  >1 publications with SIGLEC5 and Birth Weight
 Genital Diseases, Male Antibodies  >1 publications with SIGLEC5 and Genital Diseases, Male
 Weight Loss Antibodies  >1 publications with SIGLEC5 and Weight Loss

Organs/Tissues associated with anti-SIGLEC5 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >41 publications with SIGLEC5 and Blood
 Lung Antibodies  >12 publications with SIGLEC5 and Lung
 Bone Antibodies  >10 publications with SIGLEC5 and Bone
 Bone Marrow Antibodies  >10 publications with SIGLEC5 and Bone Marrow
 Spleen Antibodies  >4 publications with SIGLEC5 and Spleen
 Kidney Antibodies  >3 publications with SIGLEC5 and Kidney
 Intestine Antibodies  >2 publications with SIGLEC5 and Intestine
 Lymph Node Antibodies  >1 publications with SIGLEC5 and Lymph Node
 Thymus Antibodies  >1 publications with SIGLEC5 and Thymus
 Brain Antibodies  >1 publications with SIGLEC5 and Brain