Human Aldolase (ALDOA) activation kit by CRISPRa

Cat# GA100161

Size : 1kit

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Human Aldolase (ALDOA) activation kit by CRISPRa

SKU
GA100161
ALDOA CRISPRa kit - CRISPR gene activation of human aldolase, fructose-bisphosphate A
2 Weeks*
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ALDOA
Locus ID 226
Components

GA100161G1, Aldolase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100161G2, Aldolase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100161G3, Aldolase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000034, NM_001127617, NM_001243177, NM_184041, NM_184043, NM_001355562, NM_001355563, NM_001355564, NM_001355565, NM_001243175
UniProt ID P04075
Synonyms ALDA; GSD12; HEL-S-87p
Summary This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]
SKU Description Size
KN402576 ALDOA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.