Human IgG1 Isotype Control FES

Hen Egg Lysozyme

>1mg/ml

Human IgG1 (K214R/L234F/L235E/P331S)-kappa

CHO Cells

ICH3002

Blue ice

Designated FES (K214R/L234F/L235E/P331S), this human IgG1-kappa isotype control carries Fc mutations that reduce effector engagement, supplying an effector-attenuated, non-binding reference for human IgG1 experiments. It is used to define background signal, set flow-cytometry gating, and serve as a negative control in functional and in vivo studies. The antibody is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram to gram quantities to serve bulk and high-throughput laboratories. As a non-therapeutic, research-use-only reagent, it delivers reproducible, lot-consistent control performance across antibody-engineering and immunology workflows.

Human IgG1 with a FES mutation

This monoclonal antibody was purified using Protein A

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

BE0297, CP149, CP161, CP169, CP171, CP173, CP174, CP179

Q: What is the Human IgG1 FES isotype control used for?

A: It is a non-targeting, Fc-engineered Human IgG1 (FES) control raised against Hen Egg Lysozyme, used as a matched negative control; for research use only.

Q: Is the FES isotype control suitable for in vivo use?

A: Yes — it is supplied low-endotoxin and in vivo-grade as a negative control for in vivo studies.

Q: Can the FES isotype control be ordered in bulk?

A: Yes, it is manufactured in scalable milligram to gram quantities to match high-usage experimental antibodies.