Human Multidrug resistance-associated protein 4, ABCC4 ELISA Kit
Cat# MBS9326285-96
Size : 96-Strip-Wells
Brand : MyBiosource
Contact local distributor :
Phone : +1 850 650 7790
ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) ELISA Kit for Human
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9326285Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of MRP4 (hereafter termed "analyte") in… More details
Product Overview
Product Name
ATP-binding cassette, sub-family C (CFTR/MRP) , member 4 (ABCC4), ELISA Kit
Full Product Name
Human Multidrug resistance-associated protein 4, ABCC4 ELISA Kit
Product Gene Name
ABCC4 elisa kit
Product Synonym Names
Human Multidrug resistance-associated protein 4 (ABCC4) ELISA kit; RP11-74A12.1; EST170205; MOAT-B; MOATB; MRP4; ATP-binding cassette; sub-family C; member 4; bA464I2.1 (ATP-binding cassette; sub-family C (CFTR/MRP); member 4) ; canalicular multispecific organic anion; ATP-binding cassette; sub-family C (CFTR/MRP); member 4
Species Reactivity
Human
Assay Type
Quantitative Sandwich
Detection Range
0.625ng/ml-20ng/ml
Sensitivity
0.1ng/ml
Preparation and Storage
Store all reagents at 2-8 degree C
Other Notes
Small volumes of ABCC4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for ABCC4 purchase
MBS9326285 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ABCC4. The ELISA analytical biochemical technique of the MBS9326285 kit is based on ABCC4 antibody-ABCC4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ABCC4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ABCC4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Additional Details
NCBI/Uniprot data below describe general gene information for ABCC4. It may not necessarily be applicable to this product.
NCBI Official Full Name
multidrug resistance-associated protein 4 isoform 2
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
NCBI Official Symbol
ABCC4
NCBI Official Synonym Symbols
MRP4; MOATB; MOAT-B; EST170205
UniProt Protein Name
Multidrug resistance-associated protein 4
UniProt Synonym Protein Names
ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B
Protein Family
ABC transporter C family
UniProt Gene Name
ABCC4
UniProt Synonym Gene Names
MRP4; MOAT-B
UniProt Entry Name
MRP4_HUMAN
NCBI Protein Information
multidrug resistance-associated protein 4; MRP/cMOAT-related ABC transporter; multispecific organic anion transporter B; ATP-binding cassette sub-family C member 4; multi-specific organic anion transporter B; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily)
NCBI Summary for ABCC4
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for ABCC4
ABCC4: a widely-expressed multi-pass membrane protein. An organic anion pump involved in cellular detoxification. Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.
Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, ABC family
Chromosomal Location of Human Ortholog: 13q32
Cellular Component: membrane; basolateral plasma membrane; integral to membrane; plasma membrane; platelet dense granule membrane
Molecular Function: ATPase activity, coupled to transmembrane movement of substances; 15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding
Biological Process: response to drug; platelet activation; platelet degranulation; positive regulation of smooth muscle cell proliferation; blood coagulation; response to organic nitrogen; response to organic cyclic substance; transmembrane transport
Show more Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, ABC family
Chromosomal Location of Human Ortholog: 13q32
Cellular Component: membrane; basolateral plasma membrane; integral to membrane; plasma membrane; platelet dense granule membrane
Molecular Function: ATPase activity, coupled to transmembrane movement of substances; 15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ATP binding
Biological Process: response to drug; platelet activation; platelet degranulation; positive regulation of smooth muscle cell proliferation; blood coagulation; response to organic nitrogen; response to organic cyclic substance; transmembrane transport
Research Articles on ABCC4
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with ABCC4 elisa kit
| Products by Pathway | Pathway Diagram |
|---|---|
| ABC Transporters Pathway antibodies | ABC Transporters Pathway Diagram |
| ABC Transporters Pathway antibodies | ABC Transporters Pathway Diagram |
| ABC-family Proteins Mediated Transport Pathway antibodies | ABC-family Proteins Mediated Transport Pathway Diagram |
| Bile Secretion Pathway antibodies | Bile Secretion Pathway Diagram |
| Bile Secretion Pathway antibodies | Bile Secretion Pathway Diagram |
| Fluoropyrimidine Activity Pathway antibodies | Fluoropyrimidine Activity Pathway Diagram |
| Hemostasis Pathway antibodies | Hemostasis Pathway Diagram |
| Platelet Activation, Signaling And Aggregation Pathway antibodies | Platelet Activation, Signaling And Aggregation Pathway Diagram |
| Platelet Degranulation Pathway antibodies | Platelet Degranulation Pathway Diagram |
| Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies | Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram |
Diseases associated with ABCC4 elisa kit
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >59 publications with ABCC4 and Neoplasms |
| Drug Toxicity Antibodies | >30 publications with ABCC4 and Drug Toxicity |
| Carcinoma Antibodies | >22 publications with ABCC4 and Carcinoma |
| Cholestasis Antibodies | >16 publications with ABCC4 and Cholestasis |
| Liver Diseases Antibodies | >13 publications with ABCC4 and Liver Diseases |
| Gastrointestinal Diseases Antibodies | >10 publications with ABCC4 and Gastrointestinal Diseases |
| Inflammation Antibodies | >9 publications with ABCC4 and Inflammation |
| Adenocarcinoma Antibodies | >8 publications with ABCC4 and Adenocarcinoma |
| Lung Neoplasms Antibodies | >8 publications with ABCC4 and Lung Neoplasms |
| Neoplasms, Experimental Antibodies | >7 publications with ABCC4 and Neoplasms, Experimental |
Organs/Tissues associated with ABCC4 elisa kit
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >91 publications with ABCC4 and Blood |
| Liver Antibodies | >58 publications with ABCC4 and Liver |
| Kidney Antibodies | >55 publications with ABCC4 and Kidney |
| Brain Antibodies | >36 publications with ABCC4 and Brain |
| Vascular Antibodies | >16 publications with ABCC4 and Vascular |
| Lung Antibodies | >14 publications with ABCC4 and Lung |
| Intestine Antibodies | >12 publications with ABCC4 and Intestine |
| Muscle Antibodies | >10 publications with ABCC4 and Muscle |
| Bone Antibodies | >7 publications with ABCC4 and Bone |
| Prostate Antibodies | >6 publications with ABCC4 and Prostate |
You might also be interested by the following products:
Cat#
Description
Cond.
Price Bef. VAT