IgA, Secretory Component (Biotin)
Cat# MBS6249024-5x0,1mL
Size : 5x0.1mL
Brand : MyBiosource
IgA Secondary Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6249024MBS6249024 is a secondary antibody targeting IgA. Also known as IgA, Secretory Component (Biotin). Reactive in Human. Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
IgA, Secondary Antibody
Full Product Name
IgA, Secretory Component (Biotin)
Product Gene Name
IgA secondary antibody
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H2259
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human secretory-piece and secretory IgA. No reaction against myeloma IgA (native or reduced and alkylated). Negative against normal human IgM, myeloma IgM, normal human IgG; free kappa or gamma chains and J-chain. Typical pattern on frozen and paraffin embedded sections of intestinal and breast tissue.
Preparation and Storage
Store at -20 degree C.
Applications Tested/Suitable for IgA secondary antibody
ELISA (EIA), Immunohistochemistry (IHC)
Product References and Citations for IgA secondary antibody
1. Baldas, V. et al. (2004) Testing for anti-human transglutaminase antibodies in saliva is not useful for diagnosis of celiac disease. Clin Chem. 50: 216-9.
Other Notes
Small volumes of IgA secondary antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for IgA. It may not necessarily be applicable to this product.
NCBI Official Full Name
Ig alpha-1 chain C region
NCBI Official Synonym Full Names
immunoglobulin heavy constant alpha 1
NCBI Official Symbol
IGHA1
NCBI Official Synonym Symbols
IgA1
UniProt Protein Name
Ig alpha-1 chain C region
Protein Family
IgA-specific serine endopeptidase autotransporter
UniProt Gene Name
IGHA1
UniProt Entry Name
IGHA1_HUMAN
UniProt Comments for IgA
IGHA1: Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.
Protein type: Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: extracellular space; extracellular region
Molecular Function: antigen binding
Biological Process: retinal homeostasis; receptor-mediated endocytosis; glomerular filtration; antibacterial humoral response; immune response; protein-chromophore linkage
Show more Protein type: Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: extracellular space; extracellular region
Molecular Function: antigen binding
Biological Process: retinal homeostasis; receptor-mediated endocytosis; glomerular filtration; antibacterial humoral response; immune response; protein-chromophore linkage
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with IgA secondary antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies | Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram |
| Inflammatory Response Pathway antibodies | Inflammatory Response Pathway Diagram |
| Regulation Of Nuclear SMAD2/3 Signaling Pathway antibodies | Regulation Of Nuclear SMAD2/3 Signaling Pathway Diagram |
| Scavenging Of Heme From Plasma Pathway antibodies | Scavenging Of Heme From Plasma Pathway Diagram |
Organs/Tissues associated with IgA secondary antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >2 publications with IgA and Blood |
| Brain Antibodies | >1 publications with IgA and Brain |


