IL2 (Human) ELISpot Kit

Quantification

Entrez GeneID

Gene Name

IL2

Gene Alias

IL-2, TCGF, lymphokine

Gene Description

interleukin 2

Omim ID

Gene Ontology

Gene Summary

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq

Other Designations

T cell growth factor|aldesleukin|interleukin-2|involved in regulation of T-cell clonal expansion