• Specifications

    Product Description

    Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. ().

    Origin

    Human

    Source

    Genomic DNA

    Reactivity

    Human

    Notice

    We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.

    Regulation Status

    For research use only (RUO)

    Supplied Products

    DAPI Counterstain (1500 ng/mL ) 250 uL

    Storage Instruction

    Store at 4°C in the dark.

    Self-Attestation

    Abnova self-attests to comply with the U.S. Framework for Nucleic Acid Synthesis Screening

  • Applications

    Fluorescent In Situ Hybridization (Cell)

    Protocol Download
  • Gene Info — IL24

    Entrez GeneID

    11009

    Gene Name

    IL24

    Gene Alias

    C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7

    Gene Description

    interleukin 24

    Omim ID

    604136

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq

    Other Designations

    IL-24 splice variant delE3|IL-24 splice variant delE5|OTTHUMP00000034620|melanoma differentiation association protein 7|suppression of tumorigenicity 16 (melanoma differentiation)

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