Lipid A (E. Coli) triethylammonium salt [1246298-63-4]

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Cat# OL58744-0.1mg

Size : 0.1mg

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Brand : Biosynth

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CAS No

[1246298-63-4]

Synonyms

2-Deoxy-6-O-{2-deoxy-2-[(R)-3-(dodecanoyloxy) tetradecanoylamino]-3-O-[(R)-3-(tetradecanoyloxy) tetra decanoyl]-b-D-glucopyranosyl}- 3-O-[(R)-3-hydroxy tetra decanoyl]-2-[(R)-3-hydroxy tetra decanoylamino]-a-D-glucopyranose 1,4'-diphosphate triethylam

Product Code

OL58744

MOL file

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Chemical Formula

C₉₄H₁₇₈N₂O₂₅P₂

Molecular Weight

1,798.37 g/mol

Smiles

CCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O)NC(=O)C[C@@H](CCCCCCCCCCC)O)OC(=O)C[C@@H](CCCCCCCCCCC)O)O)CO)OP(=O)(O)[O-])OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC.[NH4+]

The Lipid A moiety of lipopolysaccharide forms the outer monolayer of the outer membrane in most Gram-negative bacteria. Escherichia coli lipid A is synthesized on the cytoplasmic side of the inner membrane by a conserved pathway of nine constitutive enzymes. Following attachment of the core oligosaccharide, nascent core-lipid A is flipped to the outer surface of the inner membrane by the ABC transporter MsbA, where the O-antigen polymer is attached. These complex glycoforms protect bacteria from antibiotics and complement-mediated lysis. The core and O-antigen domains are required for virulence and consequently are present in most clinical and environmental isolates (Raetz, 2007).

Raetz et al (2007), Lipid A Modification Systems in Gram-Negative Bacteria, Annual Review of Biochemistry, 76(1).

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TSE / BSE Statement

TSE-BSE declaration Lipid A (E. Coli) triethylammonium salt OL58744

Retest Statement

Retest Statement Lipid A (E. Coli) triethylammonium salt OL58744