LMX1B Antibody

Cat# MBS856268-0,1mL-AF488

Size : 0.1mL(AF488)

Brand : MyBiosource

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LMX1B Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS856268

MBS856268 is an antibody targeting LMX1B. Also known as LMX1B Antibody. Reactive in Human, Mouse. More details

Product Overview

Online Datasheet in PDF
Product Name
LMX1B, Antibody
Full Product Name
LMX1B Antibody
Product Gene Name
anti-LMX1B antibody
Product Synonym Names
LIM homeobox transcription factor 1 beta; LIM/homeobox protein LMX1B; LIM/homeobox protein 1.2; LMX-1.2; LMX1B
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
LMX1B antibody detects endogenous levels of total LMX1B protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
45,080 Da
OMIM
161200
3D Structure
ModBase 3D Structure for O60663
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human LMX1B.

Product Categories/Family for anti-LMX1B antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-LMX1B antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-LMX1B antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-LMX1B antibody

Western blot analysis of extracts from Jurkat cells, 293 cells and HUVEC cells, using LMX1B antibody.
Anti-LMX1B Antibody – Cat# MBS856268

Product References and Citations for anti-LMX1B antibody

Dreyer S.D., Nat. Genet. 19:47-50(1998). Vollrath D., Hum. Mol. Genet. 7:1091-1098(1998). McIntosh I., Am. J. Hum. Genet. 63:1651-1658(1998).

Other Notes

Small volumes of anti-LMX1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LMX1B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
LIM homeobox transcription factor 1-beta isoform 2
NCBI Official Synonym Full Names
LIM homeobox transcription factor 1 beta
NCBI Official Symbol
LMX1B
NCBI Official Synonym Symbols
NPS1; LMX1.2
UniProt Protein Name
LIM homeobox transcription factor 1-beta
UniProt Synonym Protein Names
LIM/homeobox protein 1.2; LMX-1.2; LIM/homeobox protein LMX1B
Protein Family
LIM/homeobox protein
UniProt Gene Name
LMX1B
UniProt Synonym Gene Names
LMX-1.2
NCBI Protein Information
LIM homeobox transcription factor 1-beta

NCBI Summary for LMX1B

This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
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UniProt Comments for LMX1B

Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LMX1B antibody

 Reference Product  PubMed Publications
 LDB1 antibody  >6 publications with LMX1B and LDB1
 TCF3 antibody  >2 publications with LMX1B and TCF3

Pathways associated with anti-LMX1B antibody

 Products by Pathway  Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram

Diseases associated with anti-LMX1B antibody

 Disease Name  Pubmed Publications
 Nail-Patella Syndrome Antibodies  >66 publications with LMX1B and Nail-Patella Syndrome
 Brain Diseases Antibodies  >12 publications with LMX1B and Brain Diseases
 Pain Antibodies  >10 publications with LMX1B and Pain
 Proteinuria Antibodies  >10 publications with LMX1B and Proteinuria
 Glaucoma 1, Open Angle, A Antibodies  >8 publications with LMX1B and Glaucoma 1, Open Angle, A
 Mental Disorders Antibodies  >8 publications with LMX1B and Mental Disorders
 Renal Insufficiency Antibodies  >7 publications with LMX1B and Renal Insufficiency
 Mental Disorders Diagnosed in Childhood Antibodies  >3 publications with LMX1B and Mental Disorders Diagnosed in Childhood
 Hematuria Antibodies  >3 publications with LMX1B and Hematuria
 Learning Disorders Antibodies  >1 publications with LMX1B and Learning Disorders

Organs/Tissues associated with anti-LMX1B antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >74 publications with LMX1B and Brain
 Eye Antibodies  >20 publications with LMX1B and Eye
 Mixed Antibodies  >1 publications with LMX1B and Mixed
 Testis Antibodies  >1 publications with LMX1B and Testis