Mouse Gamma-Glutamyltransferase 1 (gGT1) Antibody Pair Kit (with Standard)

Cat# MBS2100289-10x96

Size : 10x96Tests

Brand : MyBiosource

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Gamma-Glutamyltransferase 1 (gGT1) Antibody Pair Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2100289
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MBS2100289 is an antibody pair kit targeting gGT1. Also known as Mouse Gamma-Glutamyltransferase 1 (gGT1) Antibody Pair Kit (with Standard). Reactive in Mouse. More details

Product Overview

Online Datasheet in PDF
Product Name
Gamma-Glutamyltransferase 1 (gGT1), Antibody Pair Kit
Full Product Name
Mouse Gamma-Glutamyltransferase 1 (gGT1) Antibody Pair Kit (with Standard)
Product Gene Name
gGT1 antibody pair kit
Product Synonym Names
CD224; G-GT1; GTG; Gamma-glutamyltranspeptidase 1; Glutathione hydrolase 1; Leukotriene-C4 hydrolase;
Species Reactivity
Mouse
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates and Other Biological Fluids
Detection Range
0.625-40ng/mL
Molecular Weight
24,080 Da
OMIM
J04131 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Standard
Recombinant gGT1 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685

Product Categories/Family for gGT1 antibody pair kit

Enzyme & Kinase; Infection immunity; Hepatology
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for gGT1 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex

Other Notes

Small volumes of gGT1 antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for gGT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Gamma-glutamyltransferase 1
NCBI Official Synonym Full Names
gamma-glutamyltransferase 1
NCBI Official Symbol
GGT1
NCBI Official Synonym Symbols
GGT; GTG; CD224; GGT 1; D22S672; D22S732
UniProt Protein Name
Glutathione hydrolase 1 proenzyme
UniProt Synonym Protein Names
Gamma-glutamyltransferase 1; Gamma-glutamyltranspeptidase 1
Protein Family
Gamma-glutamyltranspeptidase
UniProt Gene Name
GGT1
UniProt Synonym Gene Names
GGT; GGT 1
NCBI Protein Information
glutathione hydrolase 1 proenzyme

NCBI Summary for gGT1

The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014]
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UniProt Comments for gGT1

Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with gGT1 antibody pair kit

 Reference Product  PubMed Publications
 GSTP1 antibody pair kit  >2 publications with gGT1 and GSTP1
 GSR antibody pair kit  >2 publications with gGT1 and GSR
 GCLC antibody pair kit  >1 publications with gGT1 and GCLC

Pathways associated with gGT1 antibody pair kit

 Products by Pathway  Pathway Diagram
 Aflatoxin Activation And Detoxification Pathway antibodies  Aflatoxin Activation And Detoxification Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Eicosanoid Synthesis Pathway antibodies  Eicosanoid Synthesis Pathway Diagram
 Glutathione Conjugation Pathway antibodies  Glutathione Conjugation Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram

Diseases associated with gGT1 antibody pair kit

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >10 publications with gGT1 and Liver Diseases
 Carcinoma Antibodies  >8 publications with gGT1 and Carcinoma
 Breast Neoplasms Antibodies  >4 publications with gGT1 and Breast Neoplasms
 Liver Neoplasms Antibodies  >4 publications with gGT1 and Liver Neoplasms
 Inflammation Antibodies  >3 publications with gGT1 and Inflammation
 Lung Neoplasms Antibodies  >3 publications with gGT1 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >2 publications with gGT1 and Neoplasms, Experimental
 Fibrosis Antibodies  >2 publications with gGT1 and Fibrosis
 Heart Diseases Antibodies  >2 publications with gGT1 and Heart Diseases
 Acute Kidney Injury Antibodies  >2 publications with gGT1 and Acute Kidney Injury

Organs/Tissues associated with gGT1 antibody pair kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >16 publications with gGT1 and Blood
 Lung Antibodies  >10 publications with gGT1 and Lung
 Kidney Antibodies  >8 publications with gGT1 and Kidney
 Skin Antibodies  >3 publications with gGT1 and Skin
 Connective Tissue Antibodies  >1 publications with gGT1 and Connective Tissue
 Eye Antibodies  >1 publications with gGT1 and Eye
 Testis Antibodies  >1 publications with gGT1 and Testis
 Uncharacterized Tissue Antibodies  >1 publications with gGT1 and Uncharacterized Tissue