Mouse Histone Deacetylase 4 (HDAC4) Antibody Pair Kit (with Standard)

Cat# MBS2103223-5x96

Size : 5x96Tests

Brand : MyBiosource

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Phone : +1 850 650 7790

Histone Deacetylase 4 (HDAC4) Antibody Pair Kit for Mouse

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2103223
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MBS2103223 is an antibody pair kit targeting HDAC4. Also known as Mouse Histone Deacetylase 4 (HDAC4) Antibody Pair Kit (with Standard). Reactive in Mouse. More details

Product Overview

Online Datasheet in PDF
Product Name
Histone Deacetylase 4 (HDAC4), Antibody Pair Kit
Full Product Name
Mouse Histone Deacetylase 4 (HDAC4) Antibody Pair Kit (with Standard)
Product Gene Name
HDAC4 antibody pair kit
Product Synonym Names
HD4; HDAC-A; HDACA
Species Reactivity
Mouse
Samples
Tissue Homogenates, Cell Lysates and Other Biological Fluids
Detection Range
0.625-40ng/mL
Molecular Weight
106,367 Da
OMIM
AF132607 mRNA
3D Structure
ModBase 3D Structure for P56524
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Standard
Recombinant HDAC4 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685

Product Categories/Family for HDAC4 antibody pair kit

Enzyme & Kinase
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for HDAC4 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex

Other Notes

Small volumes of HDAC4 antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HDAC4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
histone deacetylase 4
NCBI Official Synonym Full Names
histone deacetylase 4
NCBI Official Symbol
HDAC4
NCBI Official Synonym Symbols
HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A
UniProt Protein Name
Histone deacetylase 4
UniProt Gene Name
HDAC4
UniProt Synonym Gene Names
KIAA0288; HD4
NCBI Protein Information
histone deacetylase 4

NCBI Summary for HDAC4

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
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UniProt Comments for HDAC4

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Deacetylates HSPA1A and HSPA1B at 'Lys-77' leading to their preferential binding to co-chaperone STUB1 (PubMed:27708256).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HDAC4 antibody pair kit

 Reference Product  PubMed Publications
 HDAC3 antibody pair kit  >53 publications with HDAC4 and HDAC3
 HDAC9 antibody pair kit  >28 publications with HDAC4 and HDAC9
 MEF2C antibody pair kit  >21 publications with HDAC4 and MEF2C
 RUNX2 antibody pair kit  >18 publications with HDAC4 and RUNX2
 MEF2A antibody pair kit  >14 publications with HDAC4 and MEF2A
 MEF2D antibody pair kit  >10 publications with HDAC4 and MEF2D
 NCOR2 antibody pair kit  >5 publications with HDAC4 and NCOR2
 ANKRA2 antibody pair kit  >5 publications with HDAC4 and ANKRA2
 SUMO2 antibody pair kit  >4 publications with HDAC4 and SUMO2
 CIITA antibody pair kit  >3 publications with HDAC4 and CIITA

Pathways associated with HDAC4 antibody pair kit

 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway antibodies  Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway Diagram
 Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway antibodies  Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 FBXW7 Mutants And NOTCH1 In Cancer Pathway antibodies  FBXW7 Mutants And NOTCH1 In Cancer Pathway Diagram

Diseases associated with HDAC4 antibody pair kit

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >65 publications with HDAC4 and Neoplasms
 Cardiovascular Diseases Antibodies  >26 publications with HDAC4 and Cardiovascular Diseases
 Carcinoma Antibodies  >24 publications with HDAC4 and Carcinoma
 Nervous System Diseases Antibodies  >23 publications with HDAC4 and Nervous System Diseases
 Heart Diseases Antibodies  >17 publications with HDAC4 and Heart Diseases
 Vascular Diseases Antibodies  >15 publications with HDAC4 and Vascular Diseases
 Adenocarcinoma Antibodies  >10 publications with HDAC4 and Adenocarcinoma
 Breast Neoplasms Antibodies  >8 publications with HDAC4 and Breast Neoplasms
 Lymphoma Antibodies  >8 publications with HDAC4 and Lymphoma
 Necrosis Antibodies  >8 publications with HDAC4 and Necrosis

Organs/Tissues associated with HDAC4 antibody pair kit

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >91 publications with HDAC4 and Muscle
 Brain Antibodies  >41 publications with HDAC4 and Brain
 Heart Antibodies  >38 publications with HDAC4 and Heart
 Bone Antibodies  >29 publications with HDAC4 and Bone
 Blood Antibodies  >23 publications with HDAC4 and Blood
 Embryonic Tissue Antibodies  >18 publications with HDAC4 and Embryonic Tissue
 Liver Antibodies  >12 publications with HDAC4 and Liver
 Lung Antibodies  >11 publications with HDAC4 and Lung
 Prostate Antibodies  >10 publications with HDAC4 and Prostate
 Thyroid Antibodies  >10 publications with HDAC4 and Thyroid