MYL3 Antibody

Cat# MBS856255-0,1mL-AF488

Size : 0.1mL(AF488)

Brand : MyBiosource

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MYL3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS856255

MBS856255 is an antibody targeting MYL3. Also known as MYL3 Antibody. Reactive in Human. More details

Product Overview

Online Datasheet in PDF
Product Name
MYL3, Antibody
Full Product Name
MYL3 Antibody
Product Gene Name
anti-MYL3 antibody
Product Synonym Names
Myosin light chain 3; Myosin light chain 1; slow-twitch muscle B/ventricular isoform; MLC1SB; Ventricular/slow twitch myosin alkali light chain; Cardiac myosin light chain-1; CMLC1; MYL3
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
MYL3 antibody detects endogenous levels of total MYL3 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
21,932 Da
OMIM
160790
3D Structure
ModBase 3D Structure for P08590
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human MYL3.

Product Categories/Family for anti-MYL3 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MYL3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-MYL3 antibody
WB: 1:500~1:1000
ELISA: 1:20000

Testing Data #2 of anti-MYL3 antibody

Western blot analysis of extracts from HuvEC, K562 and Jurkat cells, using MYL3 antibody.
Anti-MYL3 Antibody – Cat# MBS856255

Product References and Citations for anti-MYL3 antibody

Gong Z., Submitted (AUG-1999). Sugano S., Nat. Genet. 36:40-45(2004). Venter J.C., Submitted (JUL-2005).

Other Notes

Small volumes of anti-MYL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MYL3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
myosin light chain 3
NCBI Official Synonym Full Names
myosin light chain 3
NCBI Official Symbol
MYL3
NCBI Official Synonym Symbols
CMH8; VLC1; VLCl; MLC1V; MLC1SB; MLC-lV/sb
UniProt Protein Name
Myosin light chain 3
UniProt Synonym Protein Names
Cardiac myosin light chain 1
Protein Family
Myosin
UniProt Gene Name
MYL3
UniProt Synonym Gene Names
MLC-lV/sb
NCBI Protein Information
myosin light chain 3

NCBI Summary for MYL3

MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
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UniProt Comments for MYL3

Regulatory light chain of myosin. Does not bind calcium.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MYL3 antibody

 Products by Pathway  Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Muscle Contraction Pathway antibodies  Muscle Contraction Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram
 Striated Muscle Contraction Pathway antibodies  Striated Muscle Contraction Pathway Diagram

Diseases associated with anti-MYL3 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >25 publications with MYL3 and Cardiovascular Diseases
 Heart Diseases Antibodies  >25 publications with MYL3 and Heart Diseases
 Cardiomyopathies Antibodies  >21 publications with MYL3 and Cardiomyopathies
 Heart Defects, Congenital Antibodies  >4 publications with MYL3 and Heart Defects, Congenital
 Hypertension Antibodies  >4 publications with MYL3 and Hypertension
 Neoplasms Antibodies  >3 publications with MYL3 and Neoplasms
 Cardiomyopathy, Familial Hypertrophic, 8 Antibodies  >3 publications with MYL3 and Cardiomyopathy, Familial Hypertrophic, 8
 Drug Toxicity Antibodies  >2 publications with MYL3 and Drug Toxicity
 Necrosis Antibodies  >1 publications with MYL3 and Necrosis
 Carcinoma, Squamous Cell Antibodies  >1 publications with MYL3 and Carcinoma, Squamous Cell

Organs/Tissues associated with anti-MYL3 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >27 publications with MYL3 and Muscle
 Heart Antibodies  >18 publications with MYL3 and Heart
 Vascular Antibodies  >3 publications with MYL3 and Vascular
 Embryonic Tissue Antibodies  >3 publications with MYL3 and Embryonic Tissue
 Kidney Antibodies  >2 publications with MYL3 and Kidney
 Bone Antibodies  >2 publications with MYL3 and Bone
 Intestine Antibodies  >1 publications with MYL3 and Intestine
 Liver Antibodies  >1 publications with MYL3 and Liver