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Reagents and instruments for immunology, cell biology and molecular biology.
 
Biovalley > NBN FISH Probe

NBN FISH Probe

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Cat# FA0222

Size : 200uL

Contact local distributor :


Phone : +1 850 650 7790

Brand : Abnova

Request more information

Contact local distributor :


Phone : +1 850 650 7790

  • Specifications

    Product Description

    Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. ().

    Origin

    Human

    Source

    Genomic DNA

    Reactivity

    Human

    Notice

    We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.

    Regulation Status

    For research use only (RUO)

    Supplied Products

    DAPI Counterstain (1500 ng/mL ) 250 uL

    Storage Instruction

    Store at 4°C in the dark.

    Self-Attestation

    Abnova self-attests to comply with the U.S. Framework for Nucleic Acid Synthesis Screening

  • Applications

    Fluorescent In Situ Hybridization (Cell)

    Protocol Download
  • Gene Info — NBN

    Entrez GeneID

    4683

    Gene Name

    NBN

    Gene Alias

    AT-V1, AT-V2, ATV, FLJ10155, MGC87362, NBS, NBS1, P95

    Gene Description

    nibrin

    Omim ID

    251260 602667

    Gene Ontology

    Hyperlink

    Gene Summary

    Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq

    Other Designations

    Nijmegen breakage syndrome 1 (nibrin)|cell cycle regulatory protein p95|p95 protein of the MRE11/RAD50 complex

  • Interactomes
    • NBN
  • Pathways
    • Homologous recombination
  • Diseases
    • Acute Disease
    • Adenocarcinoma
    • Astrocytoma
    • Ataxia telangiectasia
    • Brain Neoplasms
    • Breast cancer
    • Breast Neoplasms
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    • Central Nervous System Neoplasms
    • Chromosomal Instability
    • Chromosome Aberrations
    • Chromosome Breakage
    • Chromosome Deletion
    • Cleft Lip
    • Cleft Palate
    • Colorectal Neoplasms
    • Disease Progression
    • DNA Damage
    • DNA Repair-Deficiency Disorders
    • Esophageal Neoplasms
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    • Nijmegen Breakage Syndrome
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    • Uterine Cervical Neoplasms
    • Waldenstrom Macroglobulinemia
    • Werner syndrome

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eProcurement
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