NFYB Antibody

Cat# MBS8582816-0,1mL-PE

Size : 0.1mL(PE)

Brand : MyBiosource

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NFYB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582816

MBS8582816 is an antibody targeting NFYB. Also known as NFYB Antibody. Reactive in Human, Mouse, Rat, Bovine, Chicken, Dog, Pig. Host: Rabbit. Rabbit polyclonal antibody to NFYB More details

Product Overview

Online Datasheet in PDF
Product Name
NFYB, Polyclonal Antibody
Full Product Name
NFYB Antibody
Product Gene Name
anti-NFYB antibody
Product Synonym Names
HAP3; Nuclear transcription factor Y subunit beta; CAAT box DNA-binding protein subunit B; Nuclear transcription factor Y subunit B; NF-YB
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Chicken, Dog, Pig
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of NFYB protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
22,831 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (104510858..104532040, complement). Location: 12q22-q23
OMIM
189904
3D Structure
ModBase 3D Structure for P25208
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NFYB. The exact sequence is proprietary.

Product Categories/Family for anti-NFYB antibody

Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-NFYB antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NFYB antibody
WB: 1:500-1:1000
IHC: 1:50-1:200

Other Notes

Small volumes of anti-NFYB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NFYB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nuclear transcription factor Y subunit beta
NCBI Official Synonym Full Names
nuclear transcription factor Y, beta
NCBI Official Symbol
NFYB
NCBI Official Synonym Symbols
HAP3; CBF-A; CBF-B; NF-YB
UniProt Protein Name
Nuclear transcription factor Y subunit beta
UniProt Synonym Protein Names
CAAT box DNA-binding protein subunit B; Nuclear transcription factor Y subunit B
Protein Family
Nuclear transcription factor
UniProt Gene Name
NFYB
UniProt Synonym Gene Names
HAP3; NF-YB
UniProt Entry Name
NFYB_HUMAN
NCBI Protein Information
nuclear transcription factor Y subunit beta; Transcription factor NF-Y, B subunit; CAAT box DNA-binding protein subunit B; nuclear transcription factor Y subunit B; CCAAT-binding transcription factor subunit A

NCBI Summary for NFYB

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]
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UniProt Comments for NFYB

NFYB: Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. Belongs to the NFYB/HAP3 subunit family.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 12q22-q23

Cellular Component: nucleoplasm; CCAAT-binding factor complex; nucleus

Molecular Function: protein binding; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; protein complex binding; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; cellular lipid metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NFYB antibody

 Reference Product  PubMed Publications
 NFYA antibody  >12 publications with NFYB and NFYA
 SP1 antibody  >7 publications with NFYB and SP1
 NFYC antibody  >7 publications with NFYB and NFYC
 YBX1 antibody  >1 publications with NFYB and YBX1
 TBP antibody  >1 publications with NFYB and TBP
 EP300 antibody  >1 publications with NFYB and EP300
 CIITA antibody  >1 publications with NFYB and CIITA
 MYC antibody  >1 publications with NFYB and MYC

Pathways associated with anti-NFYB antibody

 Products by Pathway  Pathway Diagram
 Activation Of Chaperone Genes By ATF6-alpha Pathway antibodies  Activation Of Chaperone Genes By ATF6-alpha Pathway Diagram
 Activation Of Chaperones By ATF6-alpha Pathway antibodies  Activation Of Chaperones By ATF6-alpha Pathway Diagram
 Activation Of Gene Expression By SREBP (SREBF) Pathway antibodies  Activation Of Gene Expression By SREBP (SREBF) Pathway Diagram
 Activation Of Genes By ATF4 Pathway antibodies  Activation Of Genes By ATF4 Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram

Diseases associated with anti-NFYB antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with NFYB and Neoplasms
 Nervous System Diseases Antibodies  >1 publications with NFYB and Nervous System Diseases
 Seizures Antibodies  >1 publications with NFYB and Seizures
 Brain Diseases Antibodies  >1 publications with NFYB and Brain Diseases

Organs/Tissues associated with anti-NFYB antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >3 publications with NFYB and Nerve
 Brain Antibodies  >3 publications with NFYB and Brain
 Muscle Antibodies  >2 publications with NFYB and Muscle
 Embryonic Tissue Antibodies  >2 publications with NFYB and Embryonic Tissue
 Vascular Antibodies  >1 publications with NFYB and Vascular
 Heart Antibodies  >1 publications with NFYB and Heart
 Kidney Antibodies  >1 publications with NFYB and Kidney
 Stomach Antibodies  >1 publications with NFYB and Stomach
 Intestine Antibodies  >1 publications with NFYB and Intestine