Norepinephrine [51-41-2]

Norepinephrine is a hormone and neurotransmitter that is released by the adrenal medulla. It has vasoconstrictor and bronchodilator effects, as well as other actions such as increasing metabolic rate and blood pressure. Norepinephrine binds to β-adrenergic receptors on cells, causing them to release cyclic adenosine monophosphate (cAMP) in response. cAMP activates protein kinase A, which phosphorylates proteins leading to increased cell activity. The binding of norepinephrine to β-adrenergic receptors also leads to the activation of voltage-dependent calcium channels and increased calcium ion permeability. This increase in intracellular calcium ions leads to muscle contraction and relaxation of smooth muscle in the lungs, uterus, stomach, intestines and bladder. Norepinephrine can be used in a luminescence immunoassay for the measurement of noradrenaline levels in human serum or plasma samples.

Specification

English

MSDS

TSE / BSE Statement

TSE-BSE declaration Norepinephrine FN34820

Retest Statement

Retest Statement Norepinephrine FN34820