PE-Linked Monoclonal Antibody to Interferon Gamma (IFNg)
Cat# MBS2035974-0,2mL
Size : 0.2mL
Brand : MyBiosource
Contact local distributor :
Phone : +1 850 650 7790
Interferon Gamma (IFNg) Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2035974SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2035974 is an antibody targeting IFNg. Also known as PE-Linked Monoclonal Antibody to Interferon Gamma (IFNg). Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
Interferon Gamma (IFNg), Monoclonal Antibody
Full Product Name
PE-Linked Monoclonal Antibody to Interferon Gamma (IFNg)
Product Gene Name
anti-IFNg antibody
Clonality
Monoclonal
Clone Number
3#
Host
Mouse
Form/Format
Liquid; Supplied as solution form in 10 mM Tris, 150 mM NaCl, pH 8.2 , 50% glycerol , 0.05% Proclin-300.
Purity/Purification
Protein A+G Affinity Chromatography.
Concentration
0.25mg/mL (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Keep in dark place
Store at 4°C for 6 months.
Aliquot and store at -20°C for 12 months.
Stability Test:
The thermal stability is described by the loss rate.
The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed.
The loss rate is less than 5% within the expiration date under appropriate storage condition.
Avoid repeated freeze/thaw cycles.
Keep in dark place
Store at 4°C for 6 months.
Aliquot and store at -20°C for 12 months.
Stability Test:
The thermal stability is described by the loss rate.
The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed.
The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: IFNg Clone #3# (MBS2012543)
PE Conjugated Antibody: IFNg Clone #3# (MBS2035974)
PE Conjugated Antibody: IFNg Clone #3# (MBS2035974)
Matching Pairs
PE Conjugated Antibody: IFNg Clone #3# (MBS2035974)
Immunogen: IFNg (MBS2010925)
Immunogen: IFNg (MBS2010925)
OMIM
X13274 mRNA
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Monoclonal antibody preparation
Label
PE
Original Antibody
MBS2012543
Immunogen
Recombinant IFNg (His20~Cys164) expressed in E.coli.
Note
As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IFNg antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF).
Application Notes for anti-IFNg antibody
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Other Notes
Small volumes of anti-IFNg antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for IFNg. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interferon gamma
NCBI Official Synonym Full Names
interferon gamma
NCBI Official Symbol
IFNG
NCBI Official Synonym Symbols
IFG; IFI
UniProt Protein Name
Interferon gamma
UniProt Synonym Protein Names
Immune interferon
Protein Family
Interferon
UniProt Gene Name
IFNG
UniProt Synonym Gene Names
IFN-gamma
NCBI Protein Information
interferon gamma
NCBI Summary for IFNg
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
Show more UniProt Comments for IFNg
IFNG: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. Homodimer. Released primarily from activated T lymphocytes. Belongs to the type II (or gamma) interferon family.
Protein type: Cytokine; Membrane protein, integral; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: extracellular region; extracellular space
Molecular Function: cytokine activity
Biological Process: adaptive immune response; apoptosis; cell cycle arrest; cell motility; cell surface receptor linked signal transduction; humoral immune response; negative regulation of epithelial cell differentiation; negative regulation of interleukin-17 production; negative regulation of smooth muscle cell proliferation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of autophagy; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response; positive regulation of cell proliferation; positive regulation of interleukin-12 production; positive regulation of interleukin-23 production; positive regulation of killing of cells of another organism; positive regulation of membrane protein ectodomain proteolysis; positive regulation of nitric oxide biosynthetic process; positive regulation of osteoclast differentiation; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of tyrosine phosphorylation of Stat1 protein; protein import into nucleus, translocation; regulation of insulin secretion; response to virus
Disease: Aplastic Anemia; Hepatitis C Virus, Susceptibility To; Human Immunodeficiency Virus Type 1, Susceptibility To; Mycobacterium Tuberculosis, Susceptibility To; Tuberous Sclerosis 2
Show more Protein type: Cytokine; Membrane protein, integral; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: extracellular region; extracellular space
Molecular Function: cytokine activity
Biological Process: adaptive immune response; apoptosis; cell cycle arrest; cell motility; cell surface receptor linked signal transduction; humoral immune response; negative regulation of epithelial cell differentiation; negative regulation of interleukin-17 production; negative regulation of smooth muscle cell proliferation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of autophagy; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response; positive regulation of cell proliferation; positive regulation of interleukin-12 production; positive regulation of interleukin-23 production; positive regulation of killing of cells of another organism; positive regulation of membrane protein ectodomain proteolysis; positive regulation of nitric oxide biosynthetic process; positive regulation of osteoclast differentiation; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of tyrosine phosphorylation of Stat1 protein; protein import into nucleus, translocation; regulation of insulin secretion; response to virus
Disease: Aplastic Anemia; Hepatitis C Virus, Susceptibility To; Human Immunodeficiency Virus Type 1, Susceptibility To; Mycobacterium Tuberculosis, Susceptibility To; Tuberous Sclerosis 2
Research Articles on IFNg
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-IFNg antibody
| Reference Product | PubMed Publications |
|---|---|
| CD4 antibody | >108 publications with IFNg and CD4 |
| IL2 antibody | >35 publications with IFNg and IL2 |
| STAT1 antibody | >28 publications with IFNg and STAT1 |
| IFNGR1 antibody | >24 publications with IFNg and IFNGR1 |
| IL18 antibody | >20 publications with IFNg and IL18 |
| IFNGR2 antibody | >13 publications with IFNg and IFNGR2 |
| IRF1 antibody | >13 publications with IFNg and IRF1 |
| CD86 antibody | >2 publications with IFNg and CD86 |
Pathways associated with anti-IFNg antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| ATF-2 Transcription Factor Network Pathway antibodies | ATF-2 Transcription Factor Network Pathway Diagram |
| African Trypanosomiasis Pathway antibodies | African Trypanosomiasis Pathway Diagram |
| African Trypanosomiasis Pathway antibodies | African Trypanosomiasis Pathway Diagram |
| Allograft Rejection Pathway antibodies | Allograft Rejection Pathway Diagram |
| Allograft Rejection Pathway antibodies | Allograft Rejection Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Antigen Processing And Presentation Pathway antibodies | Antigen Processing And Presentation Pathway Diagram |
| Antigen Processing And Presentation Pathway antibodies | Antigen Processing And Presentation Pathway Diagram |
| Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies | Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram |
Diseases associated with anti-IFNg antibody
| Disease Name | Pubmed Publications |
|---|---|
| Necrosis Antibodies | >103 publications with IFNg and Necrosis |
| Autoimmune Diseases Antibodies | >68 publications with IFNg and Autoimmune Diseases |
| Respiratory Tract Diseases Antibodies | >51 publications with IFNg and Respiratory Tract Diseases |
| Hepatitis Antibodies | >23 publications with IFNg and Hepatitis |
| MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO Antibodies | >18 publications with IFNg and MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO |
| Lymphoproliferative Disorders Antibodies | >16 publications with IFNg and Lymphoproliferative Disorders |
| Diabetes Mellitus, Type 1 Antibodies | >13 publications with IFNg and Diabetes Mellitus, Type 1 |
| HIV Infections Antibodies | >13 publications with IFNg and HIV Infections |
| Arthritis, Rheumatoid Antibodies | >11 publications with IFNg and Arthritis, Rheumatoid |
| Hepatitis C Antibodies | >9 publications with IFNg and Hepatitis C |
Organs/Tissues associated with anti-IFNg antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >333 publications with IFNg and Blood |
| Kidney Antibodies | >27 publications with IFNg and Kidney |
| Lymph Node Antibodies | >22 publications with IFNg and Lymph Node |
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