PE-Linked Polyclonal Antibody to Interferon Tau (IFNt)

Cat# MBS2118676-0,5mL

Size : 0.5mL

Brand : MyBiosource

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Interferon Tau (IFNt) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2118676
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MBS2118676 is an antibody targeting IFNt. Also known as PE-Linked Polyclonal Antibody to Interferon Tau (IFNt). Reactive in Bovine. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Interferon Tau (IFNt), Polyclonal Antibody
Full Product Name
PE-Linked Polyclonal Antibody to Interferon Tau (IFNt)
Product Gene Name
anti-IFNt antibody
Product Synonym Names
IFN-T1; TP1; OTP; Trophoblastin; Interferon Tau-1; Trophoblast Protein 1; Trophoblast Antiluteolytic Protein; Antiluteolysin
Immunogen Sequence
Cys24~Leu1 95
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against IFNt. It has been selected for its ability to recognize IFNt in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: IFNt (MBS2112167)
PE Conjugated Antibody: IFNt (MBS2118676)
Matching Pairs
PE Conjugated Antibody: IFNt (MBS2118676)
Immunogen: IFNt (MBS2097726)
Molecular Weight
22,134 Da
3D Structure
ModBase 3D Structure for P15696
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen Sequence
Cys24~Leu195
Cross Reactivity
Cattle
Conjugation
PE

Product Categories/Family for anti-IFNt antibody

Human Gene Deletion
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-IFNt antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-IFNt antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IFNt. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interferon tau-2
NCBI Official Symbol
IFNT2
NCBI Official Synonym Symbols
IFNT; TP-1; IFNT1; IFN-tau-c2
UniProt Protein Name
Interferon tau-1
UniProt Synonym Protein Names
Antiluteolysin; Trophoblast antiluteolytic protein; Trophoblast protein 1; TP-1; Trophoblastin
Protein Family
Interferon
UniProt Gene Name
IFNT1
UniProt Synonym Gene Names
IFN-tau-1; TP-1
UniProt Entry Name
IFNT1_BOVIN
NCBI Protein Information
interferon tau-2

UniProt Comments for IFNt

Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IFNt antibody

 Reference Product  PubMed Publications
 SLC2A1 antibody  >2 publications with IFNt and SLC2A1

Organs/Tissues associated with anti-IFNt antibody

 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >2 publications with IFNt and Uterus