PE-Linked Polyclonal Antibody to Osteopontin (OPN)

Cat# MBS2118467-0,1mL

Size : 0.1mL

Brand : MyBiosource

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Osteopontin (OPN) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2118467
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MBS2118467 is an antibody targeting OPN. Also known as PE-Linked Polyclonal Antibody to Osteopontin (OPN). Reactive in Bovine. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Osteopontin (OPN), Polyclonal Antibody
Full Product Name
PE-Linked Polyclonal Antibody to Osteopontin (OPN)
Product Gene Name
anti-OPN antibody
Product Synonym Names
SPP1; BNSP; BSPI; ETA1; Secreted Phosphoprotein 1; Bone Sialoprotein I; Early T-Lymphocyte Activation 1; Nephropontin; Urinary stone protein; Uropontin
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
>=100ug/ml (lot specific)
Specificity
The antibody is a rabbit polyclonal antibody raised against OPN. It has been selected for its ability to recognize OPN in immunohistochemical staining and western blotting.
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: OPN (MBS2112037)
PE Conjugated Antibody: OPN (MBS2118467)
Molecular Weight
30,904 Da
3D Structure
ModBase 3D Structure for P31096
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Cross Reactivity
Cattle
Conjugation
PE

Product Categories/Family for anti-OPN antibody

Tumor Immunity; Bone Metabolism
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-OPN antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Other Notes

Small volumes of anti-OPN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OPN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
osteopontin
NCBI Official Symbol
SPP1
NCBI Official Synonym Symbols
OPN; OST
UniProt Protein Name
Osteopontin
UniProt Synonym Protein Names
Bone sialoprotein 1; Secreted phosphoprotein 1; SPP-1
UniProt Gene Name
SPP1
UniProt Synonym Gene Names
OPN; SPP-1
NCBI Protein Information
osteopontin

UniProt Comments for OPN

Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OPN antibody

 Reference Product  PubMed Publications
 CD44 antibody  >136 publications with OPN and CD44
 THBS1 antibody  >14 publications with OPN and THBS1
 MMP7 antibody  >11 publications with OPN and MMP7
 ITGA4 antibody  >10 publications with OPN and ITGA4
 ITGB3 antibody  >5 publications with OPN and ITGB3
 ITGA5 antibody  >5 publications with OPN and ITGA5
 ITGAV antibody  >3 publications with OPN and ITGAV
 ITGB1 antibody  >3 publications with OPN and ITGB1
 ITGA8 antibody  >2 publications with OPN and ITGA8

Pathways associated with anti-OPN antibody

 Products by Pathway  Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram

Diseases associated with anti-OPN antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >286 publications with OPN and Disease Models, Animal
 Inflammation Antibodies  >282 publications with OPN and Inflammation
 Kidney Diseases Antibodies  >241 publications with OPN and Kidney Diseases
 Fibrosis Antibodies  >171 publications with OPN and Fibrosis
 Neoplasm Metastasis Antibodies  >143 publications with OPN and Neoplasm Metastasis
 Necrosis Antibodies  >138 publications with OPN and Necrosis
 Adenocarcinoma Antibodies  >120 publications with OPN and Adenocarcinoma
 Calcinosis Antibodies  >119 publications with OPN and Calcinosis
 Heart Diseases Antibodies  >111 publications with OPN and Heart Diseases
 Neoplasms, Experimental Antibodies  >86 publications with OPN and Neoplasms, Experimental

Organs/Tissues associated with anti-OPN antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >578 publications with OPN and Blood
 Kidney Antibodies  >378 publications with OPN and Kidney
 Muscle Antibodies  >301 publications with OPN and Muscle
 Liver Antibodies  >146 publications with OPN and Liver
 Cartilage Antibodies  >125 publications with OPN and Cartilage
 Lung Antibodies  >118 publications with OPN and Lung
 Brain Antibodies  >106 publications with OPN and Brain
 Skin Antibodies  >91 publications with OPN and Skin
 Adipose Tissue Antibodies  >40 publications with OPN and Adipose Tissue
 Intestine Antibodies  >30 publications with OPN and Intestine