PJA1 Antibody
Cat# MBS153701-0,1mg
Size : 0.1mg
Brand : MyBiosource
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Phone : +1 850 650 7790
Western blot analysis of PJA1 in human brain tissue lysate with PJA1 antibody at (A) 0.25 and (B) 0.5 μg/ml.
Immunohistochemistry of PJA1 in mouse brain tissue with PJA1 antibody at 5 μg/ml.
Immunofluorescence of PJA1 in mouse brain tissue with PJA1 antibody at 20 μg/ml.
PJA1 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153701MBS153701 is an antibody targeting PJA1. Also known as PJA1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
PJA1, Polyclonal Antibody
Full Product Name
PJA1 Antibody
Product Gene Name
anti-PJA1 antibody
Product Synonym Names
Praja ring finger 1; E3 ubiquitin-protein ligase Praja-1; PRAJA1; RING finger protein 70; RNF70 ; praja ring finger 1, E3 ubiquitin protein ligase
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid; PJA1 antibody is supplied in PBS containing 0.02% sodium azide.
Purity/Purification
PJA1 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
PJA1 antibody is human, mouse and rat reactive. At least two isoforms of PJA1 are known to exist; this antibody will detect both isoforms.
Preparation and Storage
PJA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Antibody/Peptide Pairs
PJA1 peptide (MBS153792) is used for blocking the activity of PJA1 antibody (MBS153701)
Applications Tested/Suitable for anti-PJA1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Other Notes
Small volumes of anti-PJA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for PJA1. It may not necessarily be applicable to this product.
NCBI Official Full Name
E3 ubiquitin-protein ligase Praja-1 isoform a
NCBI Official Synonym Full Names
praja ring finger 1, E3 ubiquitin protein ligase
NCBI Official Symbol
PJA1
NCBI Official Synonym Symbols
RNF70; PRAJA1
UniProt Protein Name
E3 ubiquitin-protein ligase Praja-1
UniProt Synonym Protein Names
RING finger protein 70
Protein Family
E3 ubiquitin-protein ligase
UniProt Gene Name
PJA1
UniProt Synonym Gene Names
RNF70; Praja1
UniProt Entry Name
PJA1_HUMAN
NCBI Protein Information
E3 ubiquitin-protein ligase Praja-1; praja 1; RING finger protein 70
NCBI Summary for PJA1
This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked mental retardation disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Show more UniProt Comments for PJA1
PJA1: Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome. May be involved in protein sorting. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 6.3.2.-; Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system; Ligase
Chromosomal Location of Human Ortholog: Xq13.1
Cellular Component: cytoplasm
Molecular Function: protein binding; zinc ion binding; ubiquitin-protein ligase activity; ligase activity
Biological Process: protein ubiquitination; protein catabolic process
Show more Protein type: EC 6.3.2.-; Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system; Ligase
Chromosomal Location of Human Ortholog: Xq13.1
Cellular Component: cytoplasm
Molecular Function: protein binding; zinc ion binding; ubiquitin-protein ligase activity; ligase activity
Biological Process: protein ubiquitination; protein catabolic process
Research Articles on PJA1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-PJA1 antibody
| Reference Product | PubMed Publications |
|---|---|
| EFNB1 antibody | >3 publications with PJA1 and EFNB1 |
| EZH2 antibody | >2 publications with PJA1 and EZH2 |
| OPHN1 antibody | >2 publications with PJA1 and OPHN1 |
| EED antibody | >1 publications with PJA1 and EED |
| SUZ12 antibody | >1 publications with PJA1 and SUZ12 |
| MAGED1 antibody | >1 publications with PJA1 and MAGED1 |
Pathways associated with anti-PJA1 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies | Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram |
| Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies | Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
Diseases associated with anti-PJA1 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Lung Neoplasms Antibodies | >1 publications with PJA1 and Lung Neoplasms |
| Breast Neoplasms Antibodies | >1 publications with PJA1 and Breast Neoplasms |
Organs/Tissues associated with anti-PJA1 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >4 publications with PJA1 and Brain |
| Liver Antibodies | >2 publications with PJA1 and Liver |
| Vascular Antibodies | >1 publications with PJA1 and Vascular |
| Nerve Antibodies | >1 publications with PJA1 and Nerve |
| Kidney Antibodies | >1 publications with PJA1 and Kidney |
| Lung Antibodies | >1 publications with PJA1 and Lung |
| Testis Antibodies | >1 publications with PJA1 and Testis |