Quinacrine analog 34 [1411646-44-0]
Cat# T35747-5mg
Size : 5mg
Brand : TargetMol
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Quinacrine analog 34
(Synonyms: Autophagy-IN-4) Copy Product Info
Quinacrine analog 34 is a potent autophagy inhibitor (EC₅₀ = 0.5 μM, LD₅₀ = 27 μM) that upregulates the protein levels of the autophagy marker LC3-II and induces lysosomal deacidification.
Cas No. 1411646-44-0
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Purity:99.98%
Appearance:Solid
Color:White
COA HNMR LCMS
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Quinacrine analog 34 is a potent autophagy inhibitor (EC₅₀ = 0.5 μM, LD₅₀ = 27 μM) that upregulates the protein levels of the autophagy marker LC3-II and induces lysosomal deacidification. |
| Targets & IC50 | autophagy:2.5 μM (LD₅₀) |
| Synonyms | Autophagy-IN-4 |
| Molecular Weight | 358.91 |
| Formula | C20H27ClN4 |
| Cas No. | 1411646-44-0 |
| Smiles | ClC=1C=CC2=C(N=C3C(=C2NCCN4CCN(C)CC4)CCCC3)C1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 5 mg/mL (13.93 mM), Sonication is recommended. DMSO:PBS (pH 7.2) (1:1): < 1?mg/mL?(insoluble), Sonication is recommended. Ethanol: 2.5 mg/mL (6.97 mM), Sonication is recommended. DMF: 5 mg/mL (13.93 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
Ethanol/DMSO/DMF
DMSO/DMF
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||